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Vaxcyte

294 hedge funds and large institutions have $4.8B invested in Vaxcyte in 2025 Q2 according to their latest regulatory filings, with 57 funds opening new positions, 132 increasing their positions, 76 reducing their positions, and 75 closing their positions.

New
Increased
Maintained
Reduced
Closed

124% more call options, than puts

Call options by funds: $12M | Put options by funds: $5.37M

74% more repeat investments, than reductions

Existing positions increased: 132 | Existing positions reduced: 76

14% more funds holding in top 10

Funds holding in top 10: 78 (+1)

1.04% more ownership

Funds ownership: 113.3%114.35% (+1%)

7% less funds holding

Funds holding: 315294 (-21)

18% less capital invested

Capital invested by funds: $5.88B → $4.8B (-$1.09B)

24% less first-time investments, than exits

New positions opened: 57 | Existing positions closed: 75

Holders
294
Holders Change
-21
Holders Change %
-6.67%
% of All Funds
3.87%
Holding in Top 10
8
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+14.29%
% of All Funds
0.11%
New
57
Increased
132
Reduced
76
Closed
75
Calls
$12M
Puts
$5.37M
Net Calls
+$6.65M
Net Calls Change
+$2.33M
Name Holding Trade Value Shares
Change
Change in
Stake
Victory Capital Management
51
Victory Capital Management
Texas
$14.7M +$7.53M +229,800 +104%
Bank of New York Mellon
52
Bank of New York Mellon
New York
$14.6M +$1.04M +31,680 +8%
Barclays
53
Barclays
United Kingdom
$14.3M +$6.96M +212,287 +94%
Citigroup
54
Citigroup
New York
$14M -$6.29M -191,795 -31%
Aberdeen Group
55
Aberdeen Group
United Kingdom
$13.8M +$5.25M +160,170 +61%
JF
56
Jump Financial
Illinois
$13.1M +$9.95M +303,497 +303%
Walleye Capital
57
Walleye Capital
New York
$11.8M +$8.41M +256,644 +242%
Fiera Capital (Canada)
58
Fiera Capital (Canada)
Quebec, Canada
$11.5M -$176K -5,360 -1%
American Century Companies
59
American Century Companies
Missouri
$11.4M -$7.74M -236,002 -40%
Ameriprise
60
Ameriprise
Minnesota
$10.8M -$11.4M -347,910 -51%
IC
61
Ikarian Capital
Texas
$9.92M +$3.44M +105,000 +53%
TCM
62
Tang Capital Management
California
$9.75M
Raymond James Financial
63
Raymond James Financial
Florida
$9.74M +$211K +6,448 +2%
Jane Street
64
Jane Street
New York
$9.68M +$4.99M +152,359 +105%
SL
65
Siren LLC
Connecticut
$9.61M
SCM
66
Silverarc Capital Management
Massachusetts
$9.36M +$9.43M +287,796 New
Renaissance Technologies
67
Renaissance Technologies
New York
$8.75M +$2.39M +72,800 +37%
Deutsche Bank
68
Deutsche Bank
Germany
$8.55M -$30.6M -934,731 -78%
Alyeska Investment Group
69
Alyeska Investment Group
Illinois
$7.96M +$2.63M +80,135 +49%
DM
70
Deerfield Management
New York
$7.31M
Swiss National Bank
71
Swiss National Bank
Switzerland
$7.19M +$131K +4,000 +2%
Manulife (Manufacturers Life Insurance)
72
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$6.76M +$1.8M +54,858 +36%
ACM
73
Aquatic Capital Management
Illinois
$6.7M +$6.76M +206,171 New
WP
74
Woodline Partners
California
$6.5M -$29.9M -911,699 -82%
RhumbLine Advisers
75
RhumbLine Advisers
Massachusetts
$6.45M +$566K +17,257 +10%

PCVX Hedge Fund Activity: Q2 2025 in Review

294 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Vaxcyte (PCVX) for Q2 2025, worth a combined $4.8B — down 18% from $5.88B a quarter earlier.

Sellers outnumbered buyers: 75 funds closed out of PCVX and 57 opened new positions — a net loss of 18 holders — while 76 trimmed existing stakes and 132 added.

The largest buyer was T. Rowe Price Investment Management, adding an estimated $108M. The largest seller was Franklin Resources, cutting an estimated $70.5M.

  • 294 institutional investors held Vaxcyte (PCVX) as of Q2 2025, down from 315 in Q1 2025.
  • Funds reported $4.8B of Vaxcyte stock for Q2 2025, down 18% quarter-over-quarter.
  • 57 funds opened new Vaxcyte positions in Q2 2025 and 75 closed out, a net change of -18 holders.
  • The largest Vaxcyte buyer in Q2 2025 was T. Rowe Price Investment Management, an estimated $108M added.
  • The largest Vaxcyte seller in Q2 2025 was Franklin Resources, an estimated $70.5M sold.

Based on aggregated 13F filings for Q2 2025.