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Vaxcyte
PCVX

Overview Fund Activity

291 hedge funds and large institutions have $4.8B invested in Vaxcyte in 2025 Q2 according to their latest regulatory filings, with 58 funds opening new positions, 129 increasing their positions, 75 reducing their positions, and 74 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
291
Holders Change
-19
Holders Change %
-6.13%
% of All Funds
3.91%
Holding in Top 10
8
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+14.29%
% of All Funds
0.11%
New
58
Increased
129
Reduced
75
Closed
74
Calls
$12M
Puts
$5.37M
Net Calls
+$6.65M
Net Calls Change
+$2.33M

Top Buyers

1
T. Rowe Price Investment Management
1
T. Rowe Price Investment Management
Maryland
$195M
2
Janus Henderson Group
2
Janus Henderson Group
United Kingdom
$478M
3
D.E. Shaw & Co
3
D.E. Shaw & Co
New York
$100M
4
PBA
4
Paradigm Biocapital Advisors
New York
$110M
5
DTC
5
Deep Track Capital
Connecticut
$69.9M

Top Sellers

1
Franklin Resources
1
Franklin Resources
California
$30.5M
2
CC
2
Commodore Capital
New York
$0
3
AllianceBernstein
3
AllianceBernstein
Tennessee
$4.6M
4
Wellington Management Group
4
Wellington Management Group
Massachusetts
$161M
5
Capital Research Global Investors
5
Capital Research Global Investors
California
$155M
Name Holding Trade Value Shares
Change 		Shares
Change %
Victory Capital Management
51
Victory Capital Management
Texas
$14.7M +$7.47M +229,800 +104%
Bank of New York Mellon
52
Bank of New York Mellon
New York
$14.6M +$1.03M +31,680 +8%
Barclays
53
Barclays
United Kingdom
$14.3M +$6.9M +212,287 +94%
Citigroup
54
Citigroup
New York
$14M -$6.24M -191,795 -31%
Aberdeen Group
55
Aberdeen Group
United Kingdom
$13.8M +$5.21M +160,170 +61%
JF
56
Jump Financial
Illinois
$13.1M +$9.87M +303,497 +303%
Walleye Capital
57
Walleye Capital
New York
$11.8M +$8.34M +256,644 +242%
Fiera Capital (Canada)
58
Fiera Capital (Canada)
Quebec, Canada
$11.5M -$174K -5,360 -1%
American Century Companies
59
American Century Companies
Missouri
$11.4M -$7.67M -236,002 -40%
Ameriprise
60
Ameriprise
Minnesota
$10.8M -$11.3M -347,910 -51%
IC
61
Ikarian Capital
Texas
$9.92M +$3.41M +105,000 +53%
TCM
62
Tang Capital Management
California
$9.75M – – –
Raymond James Financial
63
Raymond James Financial
Florida
$9.74M +$210K +6,448 +2%
Jane Street
64
Jane Street
New York
$9.68M +$4.95M +152,359 +105%
SL
65
Siren LLC
Connecticut
$9.61M – – –
SCM
66
Silverarc Capital Management
Massachusetts
$9.36M +$9.36M +287,796 New
Renaissance Technologies
67
Renaissance Technologies
New York
$8.75M +$2.37M +72,800 +37%
Deutsche Bank
68
Deutsche Bank
Germany
$8.55M -$30.4M -934,731 -78%
Alyeska Investment Group
69
Alyeska Investment Group
Illinois
$7.96M +$2.61M +80,135 +49%
DM
70
Deerfield Management
New York
$7.31M – – –
Swiss National Bank
71
Swiss National Bank
Switzerland
$7.19M +$130K +4,000 +2%
Manulife (Manufacturers Life Insurance)
72
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$6.76M +$1.78M +54,858 +36%
ACM
73
Aquatic Capital Management
Illinois
$6.7M +$6.7M +206,171 New
WP
74
Woodline Partners
California
$6.5M -$29.6M -911,699 -82%
RhumbLine Advisers
75
RhumbLine Advisers
Massachusetts
$6.45M +$561K +17,257 +10%
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