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Vaxcyte

315 hedge funds and large institutions have $5.88B invested in Vaxcyte in 2025 Q1 according to their latest regulatory filings, with 58 funds opening new positions, 129 increasing their positions, 98 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed

44% more call options, than puts

Call options by funds: $14.1M | Put options by funds: $9.79M

32% more repeat investments, than reductions

Existing positions increased: 129 | Existing positions reduced: 98

0.35% more ownership

Funds ownership: 112.96%113.3% (+0.35%)

8% less first-time investments, than exits

New positions opened: 58 | Existing positions closed: 63

2% less funds holding

Funds holding: 323315 (-8)

42% less funds holding in top 10

Funds holding in top 10: 127 (-5)

49% less capital invested

Capital invested by funds: $11.5B → $5.88B (-$5.64B)

Holders
315
Holders Change
-8
Holders Change %
-2.48%
% of All Funds
4.22%
Holding in Top 10
7
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-41.67%
% of All Funds
0.09%
New
58
Increased
129
Reduced
98
Closed
63
Calls
$14.1M
Puts
$9.79M
Net Calls
+$4.32M
Net Calls Change
-$18.1M
Name Holding Trade Value Shares
Change
Change in
Stake
FLSM
51
Frazier Life Sciences Management
California
$20.4M
UBS AM
52
UBS AM
Illinois
$19.4M +$3.28M +41,034 +9%
EAM
53
Eventide Asset Management
Massachusetts
$17.8M +$6.94M +86,776 +23%
Principal Financial Group
54
Principal Financial Group
Iowa
$17.7M +$12.8M +160,622 +52%
Bank of New York Mellon
55
Bank of New York Mellon
New York
$15.8M -$314K -3,924 -0.9%
Millennium Management
56
Millennium Management
New York
$15.6M +$10.9M +136,851 +49%
TC
57
TwinBeech Capital
New York
$15.3M +$10M +125,021 +45%
Comerica Bank
58
Comerica Bank
Texas
$13.6M +$1.69M +21,091 +6%
Fiera Capital (Canada)
59
Fiera Capital (Canada)
Quebec, Canada
$13.6M +$28.7M +359,202 New
Squarepoint
60
Squarepoint
New York
$13M -$2.56M -31,964 -8%
Assenagon Asset Management
61
Assenagon Asset Management
Luxembourg
$12.2M +$25.9M +323,565 New
Susquehanna International Group
62
Susquehanna International Group
Pennsylvania
$12M +$15.4M +192,942 +154%
VOYA Investment Management
63
VOYA Investment Management
Georgia
$11.6M +$413K +5,169 +2%
TD Asset Management
64
TD Asset Management
Ontario, Canada
$11.5M -$2.41M -30,160 -9%
TCM
65
Tang Capital Management
California
$11.3M
SL
66
Siren LLC
Connecticut
$11.2M -$356K -4,448 -1%
Raymond James Financial
67
Raymond James Financial
Florida
$11.1M +$2.27M +28,430 +11%
Allspring Global Investments
68
Allspring Global Investments
North Carolina
$10.8M -$20.6M -257,533 -43%
TCM
69
TimesSquare Capital Management
New York
$10.6M -$10.5M -131,774 -32%
Amundi
70
Amundi
France
$10.5M -$5.07M -63,416 -16%
FTM
71
First Turn Management
California
$10.5M
Aberdeen Group
72
Aberdeen Group
United Kingdom
$10M +$3.19M +39,913 +18%
Point72 Asset Management
73
Point72 Asset Management
Connecticut
$9.26M -$459K -5,738 -2%
SVCM
74
Saturn V Capital Management
Texas
$8.77M +$2.24M +28,010 +14%
Dimensional Fund Advisors
75
Dimensional Fund Advisors
Texas
$8.74M -$5.3M -66,275 -23%

PCVX Hedge Fund Activity: Q1 2025 in Review

315 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Vaxcyte (PCVX) for Q1 2025, worth a combined $5.88B — down 49% from $11.5B a quarter earlier.

Sellers outnumbered buyers: 63 funds closed out of PCVX and 58 opened new positions — a net loss of 5 holders — while 98 trimmed existing stakes and 129 added.

The largest buyer was RA Capital Management, adding an estimated $280M. The largest seller was Goldman Sachs, cutting an estimated $158M.

  • 315 institutional investors held Vaxcyte (PCVX) as of Q1 2025, down from 323 in Q4 2024.
  • Funds reported $5.88B of Vaxcyte stock for Q1 2025, down 49% quarter-over-quarter.
  • 58 funds opened new Vaxcyte positions in Q1 2025 and 63 closed out, a net change of -5 holders.
  • The largest Vaxcyte buyer in Q1 2025 was RA Capital Management, an estimated $280M added.
  • The largest Vaxcyte seller in Q1 2025 was Goldman Sachs, an estimated $158M sold.

Based on aggregated 13F filings for Q1 2025.