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Vaxcyte

285 hedge funds and large institutions have $5.09B invested in Vaxcyte in 2025 Q3 according to their latest regulatory filings, with 40 funds opening new positions, 100 increasing their positions, 103 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

389% more call options, than puts

Call options by funds: $20.9M | Put options by funds: $4.27M

6% more capital invested

Capital invested by funds: $4.8B → $5.09B (+$292M)

3% less repeat investments, than reductions

Existing positions increased: 100 | Existing positions reduced: 103

9% less first-time investments, than exits

New positions opened: 40 | Existing positions closed: 44

3% less funds holding

Funds holding: 294285 (-9)

5.53% less ownership

Funds ownership: 114.35%108.82% (-5.5%)

13% less funds holding in top 10

Funds holding in top 10: 87 (-1)

Holders
285
Holders Change
-9
Holders Change %
-3.06%
% of All Funds
3.74%
Holding in Top 10
7
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-12.5%
% of All Funds
0.09%
New
40
Increased
100
Reduced
103
Closed
44
Calls
$20.9M
Puts
$4.27M
Net Calls
+$16.6M
Net Calls Change
+$9.96M
Name Holding Trade Value Shares
Change
Change in
Stake
Millennium Management
26
Millennium Management
New York
$34.2M -$5.16M -155,872 -14%
NHAS
27
Novo Holdings A/S
Denmark
$33M
UBS Group
28
UBS Group
Switzerland
$30.5M -$17.7M -533,280 -39%
Capital Research Global Investors
29
Capital Research Global Investors
California
$30.4M -$130M -3,928,808 -82%
SVCM
30
Saturn V Capital Management
Texas
$28.4M +$8.09M +244,220 +45%
Morgan Stanley
31
Morgan Stanley
New York
$28.3M -$1.9M -57,439 -7%
Aberdeen Group
32
Aberdeen Group
United Kingdom
$26M +$9.87M +297,886 +70%
Point72 Asset Management
33
Point72 Asset Management
Connecticut
$25.1M +$23.1M +696,843 New
Brown Advisory
34
Brown Advisory
Maryland
$24.4M +$3.48M +105,046 +18%
Comerica Bank
35
Comerica Bank
Texas
$23.6M +$5.79M +174,859 +36%
BBA
36
Baker Bros. Advisors
New York
$23.1M
Bank of America
37
Bank of America
North Carolina
$22.9M -$14.8M -447,601 -41%
LGM
38
Logos Global Management
California
$22.5M +$20.7M +625,000 New
Qube Research & Technologies (QRT)
39
Qube Research & Technologies (QRT)
United Kingdom
$19.9M -$8.47M -255,681 -32%
Ensign Peak Advisors
40
Ensign Peak Advisors
Utah
$19M -$111K -3,350 -0.6%
Voloridge Investment Management
41
Voloridge Investment Management
Florida
$18.7M -$3.76M -113,470 -18%
N
42
Nuveen
North Carolina
$17.5M -$104K -3,131 -0.6%
FLSM
43
Frazier Life Sciences Management
California
$17.1M
Bank of New York Mellon
44
Bank of New York Mellon
New York
$15.8M -$334K -10,082 -2%
PCH
45
Polar Capital Holdings
United Kingdom
$15M -$13.6M -410,265 -50%
TD Asset Management
46
TD Asset Management
Ontario, Canada
$14.4M -$4.68M -141,304 -26%
UBS AM
47
UBS AM
Illinois
$14.3M -$5.2M -156,864 -28%
Deutsche Bank
48
Deutsche Bank
Germany
$14.3M +$4.47M +134,832 +51%
Barclays
49
Barclays
United Kingdom
$14.2M -$1.47M -44,495 -10%
EAM
50
Eventide Asset Management
Massachusetts
$13.7M -$15.5M -468,811 -55%

PCVX Hedge Fund Activity: Q3 2025 in Review

285 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Vaxcyte (PCVX) for Q3 2025, worth a combined $5.09B — up 6.1% from $4.8B a quarter earlier.

Sellers outnumbered buyers: 44 funds closed out of PCVX and 40 opened new positions — a net loss of 4 holders — while 103 trimmed existing stakes and 100 added.

The largest buyer was T. Rowe Price Investment Management, adding an estimated $76.7M. The largest seller was Capital Research Global Investors, cutting an estimated $130M.

  • 285 institutional investors held Vaxcyte (PCVX) as of Q3 2025, down from 294 in Q2 2025.
  • Funds reported $5.09B of Vaxcyte stock for Q3 2025, up 6.1% quarter-over-quarter.
  • 40 funds opened new Vaxcyte positions in Q3 2025 and 44 closed out, a net change of -4 holders.
  • The largest Vaxcyte buyer in Q3 2025 was T. Rowe Price Investment Management, an estimated $76.7M added.
  • The largest Vaxcyte seller in Q3 2025 was Capital Research Global Investors, an estimated $130M sold.

Based on aggregated 13F filings for Q3 2025.