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Vaxcyte

294 hedge funds and large institutions have $4.8B invested in Vaxcyte in 2025 Q2 according to their latest regulatory filings, with 57 funds opening new positions, 132 increasing their positions, 76 reducing their positions, and 75 closing their positions.

New
Increased
Maintained
Reduced
Closed

124% more call options, than puts

Call options by funds: $12M | Put options by funds: $5.37M

74% more repeat investments, than reductions

Existing positions increased: 132 | Existing positions reduced: 76

14% more funds holding in top 10

Funds holding in top 10: 78 (+1)

1.04% more ownership

Funds ownership: 113.3%114.35% (+1%)

7% less funds holding

Funds holding: 315294 (-21)

18% less capital invested

Capital invested by funds: $5.88B → $4.8B (-$1.09B)

24% less first-time investments, than exits

New positions opened: 57 | Existing positions closed: 75

Holders
294
Holders Change
-21
Holders Change %
-6.67%
% of All Funds
3.87%
Holding in Top 10
8
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+14.29%
% of All Funds
0.11%
New
57
Increased
132
Reduced
76
Closed
75
Calls
$12M
Puts
$5.37M
Net Calls
+$6.65M
Net Calls Change
+$2.33M
Name Holding Trade Value Shares
Change
Change in
Stake
Millennium Management
26
Millennium Management
New York
$35.9M +$22.7M +691,410 +167%
Citadel Advisors
27
Citadel Advisors
Florida
$35.5M +$32.6M +994,351 +1,032%
Bank of America
28
Bank of America
North Carolina
$35.2M +$9.57M +291,859 +37%
Norges Bank
29
Norges Bank
Norway
$32.1M +$2.88M +87,832 +10%
Franklin Resources
30
Franklin Resources
California
$30.5M -$70.5M -2,149,757 -70%
Goldman Sachs
31
Goldman Sachs
New York
$30.4M -$6.97M -212,634 -19%
NHAS
32
Novo Holdings A/S
Denmark
$29.8M +$38K +1,160 +0.1%
EAM
33
Eventide Asset Management
Massachusetts
$27.6M +$12.4M +377,911 +80%
Morgan Stanley
34
Morgan Stanley
New York
$27.4M +$7.7M +234,971 +39%
PCH
35
Polar Capital Holdings
United Kingdom
$26.8M -$8.41M -256,678 -24%
Qube Research & Technologies (QRT)
36
Qube Research & Technologies (QRT)
United Kingdom
$26.3M +$26.5M +809,530 New
Royal Bank of Canada
37
Royal Bank of Canada
Ontario, Canada
$24.4M +$23.6M +719,921 +2,443%
ClearBridge Investments
38
ClearBridge Investments
New York
$21M -$18.8M -574,400 -47%
BBA
39
Baker Bros. Advisors
New York
$20.8M
Voloridge Investment Management
40
Voloridge Investment Management
Florida
$20.6M +$20.8M +633,204 New
Brown Advisory
41
Brown Advisory
Maryland
$18.6M +$55.1K +1,681 +0.3%
UBS AM
42
UBS AM
Illinois
$18M +$1.34M +41,010 +8%
SVCM
43
Saturn V Capital Management
Texas
$17.7M +$10.2M +311,926 +134%
TD Asset Management
44
TD Asset Management
Ontario, Canada
$17.5M +$7.74M +236,188 +78%
Ensign Peak Advisors
45
Ensign Peak Advisors
Utah
$17.3M -$6.95M -211,957 -28%
Lazard Asset Management
46
Lazard Asset Management
New York
$16.6M -$1.5M -45,659 -8%
TC
47
TwinBeech Capital
New York
$16.4M +$3.22M +98,283 +24%
N
48
Nuveen
North Carolina
$15.9M -$2.23M -68,063 -12%
Comerica Bank
49
Comerica Bank
Texas
$15.6M +$3.91M +119,324 +33%
FLSM
50
Frazier Life Sciences Management
California
$15.4M -$2.13M -65,000 -12%

PCVX Hedge Fund Activity: Q2 2025 in Review

294 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Vaxcyte (PCVX) for Q2 2025, worth a combined $4.8B — down 18% from $5.88B a quarter earlier.

Sellers outnumbered buyers: 75 funds closed out of PCVX and 57 opened new positions — a net loss of 18 holders — while 76 trimmed existing stakes and 132 added.

The largest buyer was T. Rowe Price Investment Management, adding an estimated $108M. The largest seller was Franklin Resources, cutting an estimated $70.5M.

  • 294 institutional investors held Vaxcyte (PCVX) as of Q2 2025, down from 315 in Q1 2025.
  • Funds reported $4.8B of Vaxcyte stock for Q2 2025, down 18% quarter-over-quarter.
  • 57 funds opened new Vaxcyte positions in Q2 2025 and 75 closed out, a net change of -18 holders.
  • The largest Vaxcyte buyer in Q2 2025 was T. Rowe Price Investment Management, an estimated $108M added.
  • The largest Vaxcyte seller in Q2 2025 was Franklin Resources, an estimated $70.5M sold.

Based on aggregated 13F filings for Q2 2025.