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Vaxcyte

315 hedge funds and large institutions have $5.88B invested in Vaxcyte in 2025 Q1 according to their latest regulatory filings, with 58 funds opening new positions, 129 increasing their positions, 98 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed

44% more call options, than puts

Call options by funds: $14.1M | Put options by funds: $9.79M

32% more repeat investments, than reductions

Existing positions increased: 129 | Existing positions reduced: 98

0.35% more ownership

Funds ownership: 112.96%113.3% (+0.35%)

8% less first-time investments, than exits

New positions opened: 58 | Existing positions closed: 63

2% less funds holding

Funds holding: 323315 (-8)

42% less funds holding in top 10

Funds holding in top 10: 127 (-5)

49% less capital invested

Capital invested by funds: $11.5B → $5.88B (-$5.64B)

Holders
315
Holders Change
-8
Holders Change %
-2.48%
% of All Funds
4.22%
Holding in Top 10
7
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-41.67%
% of All Funds
0.09%
New
58
Increased
129
Reduced
98
Closed
63
Calls
$14.1M
Puts
$9.79M
Net Calls
+$4.32M
Net Calls Change
-$18.1M
Name Holding Trade Value Shares
Change
Change in
Stake
Northern Trust
26
Northern Trust
Illinois
$42.4M -$2.96M -37,045 -3%
Pictet Asset Management
27
Pictet Asset Management
Switzerland
$42.2M +$2.63M +32,833 +3%
WP
28
Woodline Partners
California
$42M -$731K -9,145 -0.8%
PCH
29
Polar Capital Holdings
United Kingdom
$40.9M +$8.7M +108,828 +11%
UBS Group
30
UBS Group
Switzerland
$40.8M +$27.5M +343,835 +47%
DCM
31
Driehaus Capital Management
Illinois
$40.1M -$8.47M -105,970 -9%
ACA
32
Avoro Capital Advisors
New York
$37.8M -$14M -175,000 -15%
NHAS
33
Novo Holdings A/S
Denmark
$34.6M +$13.2M +165,000 +22%
Norges Bank
34
Norges Bank
Norway
$34M -$16M -200,444 -18%
D.E. Shaw & Co
35
D.E. Shaw & Co
New York
$32.8M +$7.37M +92,238 +12%
Bank of America
36
Bank of America
North Carolina
$29.9M +$25.7M +320,901 +68%
HRCM
37
Hood River Capital Management
Florida
$28.4M +$28M +350,172 +87%
DTC
38
Deep Track Capital
Connecticut
$28.3M +$60M +750,000 New
Ensign Peak Advisors
39
Ensign Peak Advisors
Utah
$28.1M +$12.6M +158,032 +27%
PBPIA
40
Pivotal bioVenture Partners Investment Advisor
California
$26.8M +$552K +6,900 +1%
PA
41
Perceptive Advisors
New York
$26.7M -$80.9M -1,011,850 -59%
Ameriprise
42
Ameriprise
Minnesota
$25.6M -$3.05M -38,192 -5%
BBA
43
Baker Bros. Advisors
New York
$24.2M +$47.3M +592,000 +1,211%
Citigroup
44
Citigroup
New York
$23.5M +$19.3M +241,871 +64%
Morgan Stanley
45
Morgan Stanley
New York
$22.9M -$6.91M -86,382 -12%
American Century Companies
46
American Century Companies
Missouri
$22.2M -$1.46M -18,213 -3%
Brown Advisory
47
Brown Advisory
Maryland
$21.5M +$1.12M +14,049 +3%
Lazard Asset Management
48
Lazard Asset Management
New York
$21.1M +$5.68M +71,030 +15%
EP
49
Eversept Partners
New York
$21M +$34.3M +429,482 +337%
N
50
Nuveen
North Carolina
$21M +$2.09M +26,182 +5%

PCVX Hedge Fund Activity: Q1 2025 in Review

315 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Vaxcyte (PCVX) for Q1 2025, worth a combined $5.88B — down 49% from $11.5B a quarter earlier.

Sellers outnumbered buyers: 63 funds closed out of PCVX and 58 opened new positions — a net loss of 5 holders — while 98 trimmed existing stakes and 129 added.

The largest buyer was RA Capital Management, adding an estimated $280M. The largest seller was Goldman Sachs, cutting an estimated $158M.

  • 315 institutional investors held Vaxcyte (PCVX) as of Q1 2025, down from 323 in Q4 2024.
  • Funds reported $5.88B of Vaxcyte stock for Q1 2025, down 49% quarter-over-quarter.
  • 58 funds opened new Vaxcyte positions in Q1 2025 and 63 closed out, a net change of -5 holders.
  • The largest Vaxcyte buyer in Q1 2025 was RA Capital Management, an estimated $280M added.
  • The largest Vaxcyte seller in Q1 2025 was Goldman Sachs, an estimated $158M sold.

Based on aggregated 13F filings for Q1 2025.