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Puma Biotechnology
PBYI

Name Holding Trade Value Shares
Change 		Change in
Stake
Adage Capital Partners
1
Adage Capital Partners
Massachusetts
$233M +$185M +5,242,519 New
Fidelity Investments
2
Fidelity Investments
Massachusetts
$160M +$127M +3,611,797 New
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$61.2M +$48.6M +1,378,567 New
Vanguard Group
4
Vanguard Group
Pennsylvania
$46M +$36.5M +1,036,387 New
Jennison Associates
5
Jennison Associates
New York
$40.6M +$32.3M +915,096 New
Wellington Management Group
6
Wellington Management Group
Massachusetts
$37.6M +$29.8M +846,495 New
BCPEM
7
Bain Capital Public Equity Management
Massachusetts
$33M +$26.2M +744,403 New
JP Morgan Chase
8
JP Morgan Chase
New York
$32.5M +$25.8M +732,666 New
TCM
9
Tekla Capital Management
Massachusetts
$31.6M +$25.1M +711,800 New
Franklin Resources
10
Franklin Resources
California
$27.7M +$22M +624,677 New
BA
11
BlackRock Advisors
Delaware
$25.2M +$20.1M +568,840 New
RG
12
Redmile Group
California
$24M +$19M +539,994 New
Federated Hermes
13
Federated Hermes
Pennsylvania
$22.5M +$17.9M +507,085 New
BFA
14
BlackRock Fund Advisors
California
$22.4M +$17.8M +504,098 New
AllianceBernstein
15
AllianceBernstein
Tennessee
$19.8M +$15.7M +446,612 New
WC
16
Weatherbie Capital
Massachusetts
$15.1M +$12M +341,417 New
State Street
17
State Street
Massachusetts
$14M +$11.1M +315,670 New
O
18
OrbiMed
New York
$13.1M +$10.4M +295,000 New
BIT
19
BlackRock Institutional Trust
California
$11.4M +$9.09M +257,825 New
Bank of New York Mellon
20
Bank of New York Mellon
New York
$11.4M +$9.05M +256,646 New
Citadel Advisors
21
Citadel Advisors
Florida
$9.95M +$7.9M +224,144 New
Westfield Capital Management
22
Westfield Capital Management
Massachusetts
$8.19M +$6.51M +184,600 New
PC
23
Polar Capital
United Kingdom
$6.66M +$5.29M +150,000 New
Northern Trust
24
Northern Trust
Illinois
$6.34M +$5.04M +142,904 New
Lord, Abbett & Co
25
Lord, Abbett & Co
New Jersey
$6.21M +$4.94M +140,076 New
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