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Puma Biotechnology
PBYI

Name Holding Trade Value Shares
Change 		Change in
Stake
Vanguard Group
1
Vanguard Group
Pennsylvania
$45.1M -$3.2M -308,709 -7%
State Street
2
State Street
Massachusetts
$35.2M -$1.72M -165,763 -5%
BlackRock
3
BlackRock
New York
$30.8M +$1.45M +140,413 +5%
FAM
4
Fred Alger Management
New York
$25.8M +$1.44M +139,062 +6%
CCM
5
Camber Capital Management
Massachusetts
$25M +$4.66M +450,000 +23%
Renaissance Technologies
6
Renaissance Technologies
New York
$15.3M +$3.9M +377,100 +35%
TCM
7
Tang Capital Management
California
$14.2M +$5.85M +565,376 +71%
PAI
8
Palo Alto Investors
California
$14M -$541K -52,266 -4%
Acadian Asset Management
9
Acadian Asset Management
Massachusetts
$13.2M +$4.05M +391,666 +45%
SI
10
Sofinnova Investments
California
$12.5M +$5.79M +559,604 +88%
Millennium Management
11
Millennium Management
New York
$12.2M -$8.03M -775,645 -40%
Goldman Sachs
12
Goldman Sachs
New York
$10.3M +$3.01M +291,227 +42%
T. Rowe Price Associates
13
T. Rowe Price Associates
Maryland
$9.44M -$1.35M -130,254 -13%
Deutsche Bank
14
Deutsche Bank
Germany
$6.71M +$1.01M +97,279 +18%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$5.5M +$565K +54,578 +12%
Arrowstreet Capital
16
Arrowstreet Capital
Massachusetts
$5.26M +$4.61M +445,767 +763%
Federated Hermes
17
Federated Hermes
Pennsylvania
$4.86M -$5.62M -542,631 -54%
RHJA
18
Rice Hall James & Associates
California
$4.75M -$113K -10,915 -2%
Nuveen
19
Nuveen
North Carolina
$4.71M -$294K -28,388 -6%
Northern Trust
20
Northern Trust
Illinois
$4.11M +$145K +13,988 +4%
Charles Schwab
21
Charles Schwab
California
$3.36M +$132K +12,735 +4%
PAM
22
Panagora Asset Management
Massachusetts
$3.09M +$1.52M +146,974 +99%
Bank of Montreal
23
Bank of Montreal
Ontario, Canada
$2.92M +$975K +94,228 +49%
Bank of America
24
Bank of America
North Carolina
$2.85M +$1.75M +169,185 +162%
JP Morgan Chase
25
JP Morgan Chase
New York
$2.84M +$2.01M +194,479 +250%
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