|
1
|
Vanguard Group
Malvern,
Pennsylvania
|
$39.1M
|
+$6.3M
|
+648,571
|
+16%
|
|
|
2
|
State Street
Boston,
Massachusetts
|
$29.9M
|
+$315K
|
+32,468
|
+0.9%
|
|
|
3
|
|
$23.8M
|
-$733K
|
-75,453
|
-3%
|
|
|
4
|
EcoR1 Capital
San Francisco,
California
|
$21.4M
|
+$24.6M
|
+2,536,156
|
New
|
|
|
5
|
Fred Alger Management
New York
|
$19.7M
|
+$5.48M
|
+563,782
|
+32%
|
|
|
6
|
Camber Capital Management
Boston,
Massachusetts
|
$16.5M
|
+$18.9M
|
+1,950,000
|
New
|
|
|
7
|
Millennium Management
New York
|
$16.4M
|
+$947K
|
+97,519
|
+5%
|
|
|
8
|
Palo Alto Investors
Palo Alto,
California
|
$11.8M
|
+$456K
|
+46,983
|
+3%
|
|
|
9
|
Renaissance Technologies
New York
|
$9.19M
|
+$9.63M
|
+991,097
|
+1,017%
|
|
|
10
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$8.74M
|
+$3.39M
|
+349,305
|
+51%
|
|
|
11
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$8.52M
|
+$1.8M
|
+184,939
|
+22%
|
|
|
12
|
Deerfield Management
New York
|
$8.13M
|
+$5.51M
|
+566,740
|
+143%
|
|
|
13
|
Acadian Asset Management
Boston,
Massachusetts
|
$7.39M
|
+$351K
|
+36,143
|
+4%
|
|
|
14
|
Tang Capital Management
San Diego,
California
|
$6.75M
|
+$4.38M
|
+450,600
|
+129%
|
|
|
15
|
|
$5.85M
|
-$725K
|
-74,616
|
-10%
|
|
|
16
|
Sofinnova Investments
Menlo Park,
California
|
$5.38M
|
+$6.2M
|
+638,026
|
New
|
|
|
17
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$4.61M
|
-$1.37M
|
-140,699
|
-20%
|
|
|
18
|
Nuveen
Charlotte,
North Carolina
|
$4.05M
|
-$7.78M
|
-800,760
|
-63%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$3.99M
|
-$909K
|
-93,606
|
-17%
|
|
|
20
|
Rice Hall James & Associates
San Diego,
California
|
$3.94M
|
-$431K
|
-44,374
|
-9%
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$3.21M
|
+$63.9K
|
+6,577
|
+2%
|
|
|
22
|
|
$2.72M
|
-$402K
|
-41,400
|
-11%
|
|
|
23
|
Charles Schwab
San Francisco,
California
|
$2.62M
|
-$272K
|
-28,027
|
-8%
|
|
|
24
|
Citadel Advisors
Miami,
Florida
|
$2.06M
|
-$2.9M
|
-299,008
|
-55%
|
|
|
25
|
Two Sigma Advisers
New York
|
$1.92M
|
-$1.09M
|
-112,200
|
-33%
|
|
