Adage Capital Partners’s Puma Biotechnology PBYI Stock Holding History

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2018 Q2	–	Sell	-322,000	Closed	-$21.9M	–	779
2018 Q1	$21.9M	Sell	322,000 -1,900,500	-86%	-$142M	0.05%	376
2017 Q4	$220M	Sell	2,222,500 -327,500	-13%	-$36.6M	0.5%	45
2017 Q3	$305M	Sell	2,550,000 -800,000	-24%	-$74.4M	0.74%	23
2017 Q2	$293M	Sell	3,350,000 -2,336,668	-41%	-$131M	0.72%	24
2017 Q1	$212M	Hold	5,686,668	–	–	0.53%	37
2016 Q4	$175M	Hold	5,686,668	–	–	0.48%	47
2016 Q3	$381M	Hold	5,686,668	–	–	1.05%	7
2016 Q2	$169M	Hold	5,686,668	–	–	0.46%	60
2016 Q1	$167M	Hold	5,686,668	–	–	0.45%	60
2015 Q4	$446M	Hold	5,686,668	–	–	1.17%	4
2015 Q3	$429M	Hold	5,686,668	–	–	1.19%	5
2015 Q2	$664M	Hold	5,686,668	–	–	1.66%	2
2015 Q1	$1.34B	Hold	5,686,668	–	–	3.27%	1
2014 Q4	$1.08B	Hold	5,686,668	–	–	2.64%	1
2014 Q3	$1.36B	Hold	5,686,668	–	–	3.36%	1
2014 Q2	$375M	Hold	5,686,668	–	–	0.97%	10
2014 Q1	$592M	Hold	5,686,668	–	–	1.62%	2
2013 Q4	$589M	Buy	5,686,668 +444,149	+8%	+$26.1M	1.56%	2
2013 Q3	$281M	Hold	5,242,519	–	–	0.81%	17
2013 Q2	$233M	Buy	+5,242,519	New	+$185M	0.72%	23