Janus Henderson Group
PBYI icon

Janus Henderson Group’s Puma Biotechnology PBYI Stock Holding History

Janus Henderson Group’s Portfolio PBYI Stock Details PBYI Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q3 		– Sell
-745,541
Closed -$2.56M – 2450
2025
Q2 		$2.56M Buy
+745,541
New +$2.38M ﹤0.01% 1172
2019
Q2 		– Sell
-2,170,423
Closed -$84.2M – 1399
2019
Q1 		$84.2M Buy
2,170,423
+308,479
+17% +$9.42M 0.05% 436
2018
Q4 		$37.9M Sell
1,861,944
-284,516
-13% -$8.54M 0.02% 608
2018
Q3 		$98.4M Sell
2,146,460
-1,155,561
-35% -$55.7M 0.05% 404
2018
Q2 		$195M Sell
3,302,021
-1,180,285
-26% -$68.4M 0.11% 232
2018
Q1 		$305M Buy
4,482,306
+126,663
+3% +$9.48M 0.18% 154
2017
Q4 		$431M Buy
4,355,643
+2,464,742
+130% +$276M 0.26% 104
2017
Q3 		$226M Buy
1,890,901
+33,270
+2% +$3.09M 0.15% 195
2017
Q2 		$162M Buy
+1,857,631
New +$104M 0.11% 242
2015
Q4 		– Sell
-2,379
Closed -$179K – 843
2015
Q3 		$179K Hold
2,379
– – ﹤0.01% 811
2015
Q2 		$277K Buy
+2,379
New +$431K ﹤0.01% 825

Other funds holding PBYI

ACA
Acorn Capital Advisors New York $366M AUM 474.6% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
Renaissance Technologies
Renaissance Technologies New York $72.6B AUM 54.88% 1-Year Est. Return
Acadian Asset Management
Acadian Asset Management Boston, Massachusetts $84.2B AUM 55.88% 1-Year Est. Return
American Century Companies
American Century Companies Kansas City, Missouri $226B AUM 44.75% 1-Year Est. Return
Dimensional Fund Advisors
Dimensional Fund Advisors Austin, Texas $552B AUM 44.19% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return
Russell Investments Group
Russell Investments Group London, United Kingdom $114B AUM 41.71% 1-Year Est. Return
Connor, Clark & Lunn Investment Management (CC&L)
Connor, Clark & Lunn Investment Management (CC&L) Vancouver, British Columbia, Canada $52.8B AUM 58.98% 1-Year Est. Return

Janus Henderson Group's PBYI Position: Q3 2025 in Review

Janus Henderson Group sold out of Puma Biotechnology (PBYI) in Q3 2025, closing a stake of 745,541 shares — an estimated $2.56M sold.

Janus Henderson Group first reported a position in PBYI in Q2 2015 and held it in 11 quarters. The position peaked at $431M in Q4 2017. 132 funds tracked by Wall St. Rank hold PBYI as of Q3 2025.

  • Janus Henderson Group reported no remaining Puma Biotechnology position as of Q3 2025 after selling out during the quarter.
  • Janus Henderson Group sold 745,541 Puma Biotechnology shares in Q3 2025, an estimated $2.56M.
  • Janus Henderson Group first reported a position in Puma Biotechnology in Q2 2015 and held it in 11 quarters.
  • Janus Henderson Group's Puma Biotechnology position peaked at $431M in Q4 2017.
  • 132 funds tracked by Wall St. Rank held Puma Biotechnology as of Q3 2025.

Based on Janus Henderson Group's 13F filing for Q3 2025, filed 14 Nov 2025.