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Opko Health

233 hedge funds and large institutions have $304M invested in Opko Health in 2025 Q3 according to their latest regulatory filings, with 29 funds opening new positions, 77 increasing their positions, 53 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,936% more call options, than puts

Call options by funds: $4.26M | Put options by funds: $209K

93% more first-time investments, than exits

New positions opened: 29 | Existing positions closed: 15

45% more repeat investments, than reductions

Existing positions increased: 77 | Existing positions reduced: 53

12% more capital invested

Capital invested by funds: $270M → $304M (+$33.2M)

5% more funds holding

Funds holding: 222233 (+11)

1.14% less ownership

Funds ownership: 25.87%24.73% (-1.1%)

Holders
233
Holders Change
+11
Holders Change %
+4.95%
% of All Funds
3.06%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
29
Increased
77
Reduced
53
Closed
15
Calls
$4.26M
Puts
$209K
Net Calls
+$4.05M
Net Calls Change
+$847K
Name Holding Trade Value Shares
Change
Change in
Stake
Optiver Holding
201
Optiver Holding
Netherlands
$4.27K +$3.79K +2,756 New
SAM
202
Smartleaf Asset Management
Massachusetts
$4.05K +$3.13K +2,283 +482%
CA
203
CoreCap Advisors
Michigan
$2.48K
Rockefeller Capital Management
204
Rockefeller Capital Management
New York
$2.17K +$1.92K +1,401 New
PP
205
PFS Partners
New Jersey
$1.71K
US Bancorp
206
US Bancorp
Minnesota
$1.71K +$687 +500 +83%
AS
207
Altshuler Shaham
Israel
$1.69K -$29.3K -21,339 -95%
MCM
208
MAI Capital Management
Ohio
$1.55K
SL
209
Salomon & Ludwin
Virginia
$1.48K -$34 -25 -3%
TWD
210
True Wealth Design
Ohio
$1.34K +$1.17K +853 +6,562%
RIL
211
Rothschild Investment LLC
Illinois
$1.05K +$383 +279 +70%
IA
212
IFP Advisors
Florida
$947 +$236 +172 +39%
PFBT
213
Parkside Financial Bank & Trust
Missouri
$613 +$542 +395 New
PAI
214
Pittenger & Anderson Inc
Nebraska
$388
Northwestern Mutual Wealth Management
215
Northwestern Mutual Wealth Management
Wisconsin
$352
GRP
216
Global Retirement Partners
California
$310
MWA
217
Medallion Wealth Advisors
Connecticut
$310
TFA
218
Transamerica Financial Advisors
Florida
$290 +$257 +187 New
HIA
219
Harbor Investment Advisory
Maryland
$279
SIC
220
Salem Investment Counselors
North Carolina
$155
RFP
221
Root Financial Partners
California
$155 +$137 +100 New
BCM
222
Boreal Capital Management
Florida
$107
SS
223
SBI Securities
Japan
$82 -$54 -39 -42%
LFG
224
Larson Financial Group
Missouri
$62 -$4.12K -3,000 -99%
ASN
225
Advisory Services Network
Georgia
$36 +$32 +23 New

OPK Hedge Fund Activity: Q3 2025 in Review

233 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Opko Health (OPK) for Q3 2025, worth a combined $304M — up 12% from $270M a quarter earlier.

Buyers outnumbered sellers: 29 funds opened new OPK positions and 15 closed out — a net gain of 14 holders — while 77 added to existing stakes and 53 trimmed.

The largest buyer was Whitefort Capital Management, adding an estimated $4.29M. The largest seller was Weiss Asset Management, cutting an estimated $4.98M.

  • 233 institutional investors held Opko Health (OPK) as of Q3 2025, up from 222 in Q2 2025.
  • Funds reported $304M of Opko Health stock for Q3 2025, up 12% quarter-over-quarter.
  • 29 funds opened new Opko Health positions in Q3 2025 and 15 closed out, a net change of +14 holders.
  • The largest Opko Health buyer in Q3 2025 was Whitefort Capital Management, an estimated $4.29M added.
  • The largest Opko Health seller in Q3 2025 was Weiss Asset Management, an estimated $4.98M sold.

Based on aggregated 13F filings for Q3 2025.