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Opko Health

233 hedge funds and large institutions have $304M invested in Opko Health in 2025 Q3 according to their latest regulatory filings, with 29 funds opening new positions, 77 increasing their positions, 53 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,936% more call options, than puts

Call options by funds: $4.26M | Put options by funds: $209K

93% more first-time investments, than exits

New positions opened: 29 | Existing positions closed: 15

45% more repeat investments, than reductions

Existing positions increased: 77 | Existing positions reduced: 53

12% more capital invested

Capital invested by funds: $270M → $304M (+$33.2M)

5% more funds holding

Funds holding: 222233 (+11)

1.14% less ownership

Funds ownership: 25.87%24.73% (-1.1%)

Holders
233
Holders Change
+11
Holders Change %
+4.95%
% of All Funds
3.06%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
29
Increased
77
Reduced
53
Closed
15
Calls
$4.26M
Puts
$209K
Net Calls
+$4.05M
Net Calls Change
+$847K
Name Holding Trade Value Shares
Change
Change in
Stake
Ameriprise
76
Ameriprise
Minnesota
$148K +$661 +481 +0.5%
3F
77
360 Financial
Minnesota
$142K +$3.43K +2,500 +3%
HCM
78
Hollencrest Capital Management
California
$140K
SG Americas Securities
79
SG Americas Securities
New York
$135K -$164K -119,358 -58%
Teacher Retirement System of Texas
80
Teacher Retirement System of Texas
Texas
$126K +$41.5K +30,248 +59%
Creative Planning
81
Creative Planning
Kansas
$125K +$77.3K +56,304 +230%
Osaic Holdings
82
Osaic Holdings
Arizona
$124K -$10.6K -7,701 -8%
Verition Fund Management
83
Verition Fund Management
Connecticut
$123K +$39.7K +28,884 +57%
Mercer Global Advisors
84
Mercer Global Advisors
Colorado
$121K +$52.7K +38,352 +97%
Wealth Enhancement Advisory Services
85
Wealth Enhancement Advisory Services
Minnesota
$117K +$53.2K +38,755 +105%
KK
86
KLP Kapitalforvaltning
Norway
$115K
CSS
87
Cubist Systematic Strategies
Connecticut
$112K -$84.5K -61,532 -46%
ProShare Advisors
88
ProShare Advisors
Maryland
$109K -$5.24K -3,815 -5%
Mariner
89
Mariner
Kansas
$107K +$61.7K +44,914 +186%
CAPTRUST Financial Advisors
90
CAPTRUST Financial Advisors
North Carolina
$105K +$35.8K +26,099 +62%
CFP
91
Cascade Financial Partners
California
$103K
Pictet Asset Management
92
Pictet Asset Management
Switzerland
$102K
AAP
93
Arax Advisory Partners
Colorado
$98.9K +$87.6K +63,780 New
Raymond James Financial
94
Raymond James Financial
Florida
$96.4K -$5.45K -3,965 -6%
Public Employees Retirement Association of Colorado
95
Public Employees Retirement Association of Colorado
Colorado
$95K
Renaissance Technologies
96
Renaissance Technologies
New York
$92.5K +$29.7K +21,600 +57%
BJL
97
Brighton Jones LLC
Washington
$92.1K +$28.2K +20,510 +53%
Cetera Investment Advisers
98
Cetera Investment Advisers
Illinois
$91.5K -$2.07K -1,506 -2%
KPWS
99
Kestra Private Wealth Services
Texas
$90.6K
PNC Financial Services Group
100
PNC Financial Services Group
Pennsylvania
$88.4K +$343 +250 +0.4%

OPK Hedge Fund Activity: Q3 2025 in Review

233 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Opko Health (OPK) for Q3 2025, worth a combined $304M — up 12% from $270M a quarter earlier.

Buyers outnumbered sellers: 29 funds opened new OPK positions and 15 closed out — a net gain of 14 holders — while 77 added to existing stakes and 53 trimmed.

The largest buyer was Whitefort Capital Management, adding an estimated $4.29M. The largest seller was Weiss Asset Management, cutting an estimated $4.98M.

  • 233 institutional investors held Opko Health (OPK) as of Q3 2025, up from 222 in Q2 2025.
  • Funds reported $304M of Opko Health stock for Q3 2025, up 12% quarter-over-quarter.
  • 29 funds opened new Opko Health positions in Q3 2025 and 15 closed out, a net change of +14 holders.
  • The largest Opko Health buyer in Q3 2025 was Whitefort Capital Management, an estimated $4.29M added.
  • The largest Opko Health seller in Q3 2025 was Weiss Asset Management, an estimated $4.98M sold.

Based on aggregated 13F filings for Q3 2025.