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Opko Health

233 hedge funds and large institutions have $304M invested in Opko Health in 2025 Q3 according to their latest regulatory filings, with 29 funds opening new positions, 77 increasing their positions, 53 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,936% more call options, than puts

Call options by funds: $4.26M | Put options by funds: $209K

93% more first-time investments, than exits

New positions opened: 29 | Existing positions closed: 15

45% more repeat investments, than reductions

Existing positions increased: 77 | Existing positions reduced: 53

12% more capital invested

Capital invested by funds: $270M → $304M (+$33.2M)

5% more funds holding

Funds holding: 222233 (+11)

1.14% less ownership

Funds ownership: 25.87%24.73% (-1.1%)

Holders
233
Holders Change
+11
Holders Change %
+4.95%
% of All Funds
3.06%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
29
Increased
77
Reduced
53
Closed
15
Calls
$4.26M
Puts
$209K
Net Calls
+$4.05M
Net Calls Change
+$847K
Name Holding Trade Value Shares
Change
Change in
Stake
Mirae Asset Global ETFs Holdings
51
Mirae Asset Global ETFs Holdings
Hong Kong
$296K -$9.56K -6,962 -4%
State Board of Administration of Florida Retirement System
52
State Board of Administration of Florida Retirement System
Florida
$273K
GI
53
GAMCO Investors
Connecticut
$271K
GF
54
Gabelli Funds
New York
$264K
Simplex Trading
55
Simplex Trading
Illinois
$233K +$207K +150,566 New
SP
56
SIH Partners
Delaware
$233K +$111K +80,706 +116%
IIM
57
INTECH Investment Management
Florida
$222K +$2.33K +1,699 +1%
TA
58
Teton Advisors
New York
$220K
SOW
59
State of Wyoming
Wyoming
$211K +$74.1K +53,947 +66%
New York State Common Retirement Fund
60
New York State Common Retirement Fund
New York
$203K +$96.3K +70,100 +115%
ASRS
61
Arizona State Retirement System
Arizona
$199K +$55.5K +40,414 +46%
Carson Wealth (CWM LLC)
62
Carson Wealth (CWM LLC)
Nebraska
$193K +$140K +102,184 +452%
TSS
63
Two Sigma Securities
New York
$188K +$166K +121,094 New
BNP Paribas Financial Markets
64
BNP Paribas Financial Markets
France
$183K -$636K -463,362 -80%
CAG
65
Csenge Advisory Group
Florida
$181K +$1 +1 +0%
HWP
66
Highline Wealth Partners
California
$181K +$1 +1 +0%
HI
67
Humankind Investments
New York
$178K +$7.34K +5,345 +5%
GIM
68
Glenmede Investment Management
Pennsylvania
$176K +$911 +663 +0.6%
Comerica Bank
69
Comerica Bank
Texas
$174K
VanEck Associates
70
VanEck Associates
New York
$173K -$9.91K -7,215 -6%
PFSRSONJ
71
Police & Firemen's Retirement System of New Jersey
New Jersey
$159K +$34.3K +24,948 +32%
PF
72
Phoenix Financial
Israel
$156K
RFWA
73
RPg Family Wealth Advisory
Massachusetts
$153K +$136K +98,990 New
GCM
74
Graham Capital Management
Connecticut
$152K -$2.49M -1,812,763 -95%
Cambridge Investment Research Advisors
75
Cambridge Investment Research Advisors
Iowa
$150K -$9.06K -6,600 -6%

OPK Hedge Fund Activity: Q3 2025 in Review

233 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Opko Health (OPK) for Q3 2025, worth a combined $304M — up 12% from $270M a quarter earlier.

Buyers outnumbered sellers: 29 funds opened new OPK positions and 15 closed out — a net gain of 14 holders — while 77 added to existing stakes and 53 trimmed.

The largest buyer was Whitefort Capital Management, adding an estimated $4.29M. The largest seller was Weiss Asset Management, cutting an estimated $4.98M.

  • 233 institutional investors held Opko Health (OPK) as of Q3 2025, up from 222 in Q2 2025.
  • Funds reported $304M of Opko Health stock for Q3 2025, up 12% quarter-over-quarter.
  • 29 funds opened new Opko Health positions in Q3 2025 and 15 closed out, a net change of +14 holders.
  • The largest Opko Health buyer in Q3 2025 was Whitefort Capital Management, an estimated $4.29M added.
  • The largest Opko Health seller in Q3 2025 was Weiss Asset Management, an estimated $4.98M sold.

Based on aggregated 13F filings for Q3 2025.