MREO

Mereo BioPharma
MREO

Overview Fund Activity

89 hedge funds and large institutions have $250M invested in Mereo BioPharma in 2025 Q1 according to their latest regulatory filings, with 13 funds opening new positions, 27 increasing their positions, 21 reducing their positions, and 14 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
89
Holders Change
-1
Holders Change %
-1.11%
% of All Funds
1.21%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
13
Increased
27
Reduced
21
Closed
14
Calls
$3.5M
Puts
$1.75M
Net Calls
+$1.75M
Net Calls Change
+$564K

Top Buyers

1
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$12.9M
2
FLSM
Frazier Life Sciences Management
California
+$6.12M
3
Aberdeen Group
Aberdeen Group
United Kingdom
+$4.92M
4
SSA
Schonfeld Strategic Advisors
New York
+$2.47M
5
Fidelity Investments
Fidelity Investments
Massachusetts
+$1.71M

Top Sellers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$15.8M
2
Millennium Management
Millennium Management
New York
-$8.03M
3
RSCM
Rock Springs Capital Management
Maryland
-$6.56M
4
UBS Group
UBS Group
Switzerland
-$3.86M
5
Morgan Stanley
Morgan Stanley
New York
-$3.09M
Name Holding Trade Value Shares
Change 		Shares
Change %
State Street
51
State Street
Massachusetts
$103K -$3.21K -1,426 -3%
VIA
52
Virtus Investment Advisers
Connecticut
$99K +$99K +44,007 New
CHAM
53
Clear Harbor Asset Management
Connecticut
$94.5K – – –
Ameriprise
54
Ameriprise
Minnesota
$87.8K -$125K -55,426 -59%
PI
55
PFG Investments
New York
$84.2K -$4.5K -2,000 -5%
Point72 Asset Management
56
Point72 Asset Management
Connecticut
$80.6K +$80.6K +35,816 New
Group One Trading
57
Group One Trading
Illinois
$77.1K +$77.1K +34,281 New
AF
58
Avanza Fonder
Sweden
$66.6K +$20.2K +8,521 +43%
Two Sigma Advisers
59
Two Sigma Advisers
New York
$65.9K +$65.9K +29,300 New
CC
60
Centiva Capital
New York
$56.3K – – –
QC
61
Quadrature Capital
United Kingdom
$51.2K +$51.2K +22,687 New
GSEP
62
Golden State Equity Partners
California
$44.8K -$6.08K -2,700 -12%
OIA
63
OneDigital Investment Advisors
Kansas
$41.2K – – –
Squarepoint
64
Squarepoint
New York
$40.3K -$12.9K -5,736 -24%
SSIM
65
Sheets Smith Investment Management
Texas
$38K – – –
HF
66
HRT Financial
New York
$35K +$35K +15,713 New
SWP
67
Significant Wealth Partners
Illinois
$31K +$6.67K +2,966 +27%
HSBC Holdings
68
HSBC Holdings
United Kingdom
$29.8K – – –
NFSG
69
Newbridge Financial Services Group
Florida
$24.8K +$675 +300 +3%
LFAS
70
Level Four Advisory Services
Texas
$22.5K – – –
ACM
71
ADAR1 Capital Management
Texas
$22.5K – – –
GI
72
GAMMA Investing
California
$18.9K -$1.4K -621 -7%
RhumbLine Advisers
73
RhumbLine Advisers
Massachusetts
$14.8K -$1.46K -649 -9%
Simplex Trading
74
Simplex Trading
Illinois
$9K -$111K -50,982 -93%
AAP
75
Arax Advisory Partners
Colorado
$9K – – –
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3
4 5