|
1
|
Capital Research Global Investors
Los Angeles,
California
|
$383M
|
+$65.6M
|
+373,359
|
+37%
|
|
|
2
|
Baker Bros. Advisors
New York
|
$327M
|
+$97.2M
|
+553,594
|
+90%
|
|
|
3
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$159M
|
+$67.1M
|
+382,109
|
+205%
|
|
|
4
|
Avoro Capital Advisors
New York
|
$137M
|
+$86M
|
+489,536
|
New
|
|
|
5
|
|
$137M
|
+$29.7M
|
+169,406
|
+53%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$129M
|
+$30.9M
|
+175,770
|
+61%
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$95.8M
|
-$20.7M
|
-117,865
|
-26%
|
|
|
8
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$95.7M
|
+$2.95M
|
+16,800
|
+5%
|
|
|
9
|
EcoR1 Capital
San Francisco,
California
|
$55.8M
|
+$35M
|
+199,500
|
New
|
|
|
10
|
HealthCor Management
New York
|
$55.2M
|
+$34.6M
|
+197,281
|
New
|
|
|
11
|
Victory Capital Management
San Antonio,
Texas
|
$51.5M
|
-$3.29M
|
-18,735
|
-9%
|
|
|
12
|
AllianceBernstein
Nashville,
Tennessee
|
$49.3M
|
-$17.2M
|
-98,126
|
-36%
|
|
|
13
|
Jennison Associates
New York
|
$45.3M
|
-$11.7M
|
-66,873
|
-29%
|
|
|
14
|
OppenheimerFunds
New York
|
$37.7M
|
+$23.7M
|
+134,940
|
New
|
|
|
15
|
Capital World Investors
Los Angeles,
California
|
$36.5M
|
+$12.9M
|
+73,500
|
+129%
|
|
|
16
|
Boxer Capital
San Diego,
California
|
$26.6M
|
+$16.7M
|
+95,000
|
New
|
|
|
17
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$25.8M
|
+$5.62M
|
+31,993
|
+53%
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$25.4M
|
+$2.99M
|
+17,023
|
+23%
|
|
|
19
|
PointState Capital
New York
|
$23.7M
|
+$14.9M
|
+84,600
|
New
|
|
|
20
|
Geode Capital Management
Boston,
Massachusetts
|
$22.4M
|
+$5.01M
|
+28,514
|
+55%
|
|
|
21
|
Fidelity Investments
Boston,
Massachusetts
|
$17.8M
|
-$27.6M
|
-157,257
|
-71%
|
|
|
22
|
Vivo Capital
Palo Alto,
California
|
$17.4M
|
+$6.15M
|
+35,000
|
+129%
|
|
|
23
|
Adage Capital Partners
Boston,
Massachusetts
|
$14M
|
-$35.1M
|
-200,000
|
-80%
|
|
|
24
|
|
$14M
|
+$878K
|
+5,000
|
+11%
|
|
|
25
|
Millennium Management
New York
|
$13M
|
-$8.04M
|
-45,786
|
-50%
|
|
