|
1
|
Janus Henderson Group
London,
|
$672M
|
-$24.6M
|
-140,611
|
-5%
|
|
|
2
|
Baker Bros. Advisors
New York
|
$456M
|
+$74.3M
|
+424,685
|
+27%
|
|
|
3
|
Avoro Capital Advisors
New York
|
$437M
|
+$58.4M
|
+333,888
|
+21%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$364M
|
+$246K
|
+1,404
|
+0.1%
|
|
|
5
|
|
$281M
|
+$31.5M
|
+179,836
|
+17%
|
|
|
6
|
|
$256M
|
+$106M
|
+605,741
|
+121%
|
|
|
7
|
|
$189M
|
+$88.5M
|
+505,706
|
+163%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$162M
|
+$10.2M
|
+58,473
|
+9%
|
|
|
9
|
Fidelity Investments
Boston,
Massachusetts
|
$145M
|
+$32.3M
|
+184,785
|
+42%
|
|
|
10
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$89.9M
|
+$38.2M
|
+218,356
|
+128%
|
|
|
11
|
AllianceBernstein
Nashville,
Tennessee
|
$78.6M
|
-$3.71M
|
-21,223
|
-6%
|
|
|
12
|
Geode Capital Management
Boston,
Massachusetts
|
$77.8M
|
+$6.97M
|
+39,817
|
+13%
|
|
|
13
|
Erste Asset Management
Vienna,
Austria
|
$75.3M
|
+$13.1M
|
+74,600
|
+30%
|
|
|
14
|
Bain Capital Life Sciences Investors
Boston,
Massachusetts
|
$75.1M
|
+$56.8M
|
+324,619
|
New
|
|
|
15
|
Artisan Partners
Milwaukee,
Wisconsin
|
$68.6M
|
+$2.87M
|
+16,390
|
+6%
|
|
|
16
|
|
$50.2M
|
+$19.8M
|
+113,432
|
+110%
|
|
|
17
|
AlpInvest Partners
Amsterdam,
Netherlands
|
$48.9M
|
+$37M
|
+211,488
|
New
|
|
|
18
|
RA Capital Management
Boston,
Massachusetts
|
$47.3M
|
–
|
–
|
–
|
|
|
19
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$45.9M
|
+$315K
|
+1,800
|
+0.9%
|
|
|
20
|
Group One Trading
Chicago,
Illinois
|
$44.4M
|
+$20.3M
|
+116,243
|
+154%
|
|
|
21
|
TCG Crossover Management
Palo Alto,
California
|
$41.6M
|
–
|
–
|
–
|
|
|
22
|
Pictet Asset Management
Carouge,
Switzerland
|
$39.6M
|
+$10.5M
|
+59,740
|
+54%
|
|
|
23
|
|
$35.2M
|
-$3.47M
|
-19,855
|
-12%
|
|
|
24
|
Perceptive Advisors
New York
|
$35M
|
+$4.64M
|
+26,514
|
+21%
|
|
|
25
|
|
$33.7M
|
-$990K
|
-5,659
|
-4%
|
|
