|
1
|
Janus Henderson Group
London,
|
$695M
|
-$70.9M
|
-300,768
|
-10%
|
|
|
2
|
Baker Bros. Advisors
New York
|
$526M
|
–
|
–
|
–
|
|
|
3
|
Avoro Capital Advisors
New York
|
$519M
|
+$13.1M
|
+55,556
|
+3%
|
|
|
4
|
|
$474M
|
+$158M
|
+669,259
|
+61%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$446M
|
+$22.2M
|
+94,064
|
+6%
|
|
|
6
|
|
$323M
|
-$512K
|
-2,171
|
-0.2%
|
|
|
7
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$214M
|
+$97.7M
|
+414,484
|
+107%
|
|
|
8
|
Fidelity Investments
Boston,
Massachusetts
|
$191M
|
+$20.9M
|
+88,749
|
+14%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$167M
|
-$17.9M
|
-75,801
|
-11%
|
|
|
10
|
Perceptive Advisors
New York
|
$115M
|
+$65.7M
|
+278,802
|
+184%
|
|
|
11
|
Artisan Partners
Milwaukee,
Wisconsin
|
$107M
|
+$24.8M
|
+105,229
|
+35%
|
|
|
12
|
|
$106M
|
-$98.5M
|
-418,144
|
-51%
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$92.6M
|
+$2.5M
|
+10,602
|
+3%
|
|
|
14
|
|
$77.1M
|
+$32.2M
|
+136,688
|
+90%
|
|
|
15
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$76.4M
|
+$20.7M
|
+87,762
|
+44%
|
|
|
16
|
Erste Asset Management
Vienna,
Austria
|
$66.6M
|
-$17.5M
|
-74,375
|
-23%
|
|
|
17
|
RA Capital Management
Boston,
Massachusetts
|
$54.6M
|
–
|
–
|
–
|
|
|
18
|
Bain Capital Life Sciences Investors
Boston,
Massachusetts
|
$52.6M
|
-$30.1M
|
-127,624
|
-39%
|
|
|
19
|
Pictet Asset Management
Carouge,
Switzerland
|
$48.4M
|
+$3.06M
|
+12,998
|
+8%
|
|
|
20
|
Armistice Capital
New York
|
$44.9M
|
+$27.8M
|
+118,000
|
+236%
|
|
|
21
|
TCG Crossover Management
Palo Alto,
California
|
$39.9M
|
-$7.22M
|
-30,634
|
-17%
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
$35.1M
|
-$789K
|
-3,348
|
-2%
|
|
|
23
|
Tao Capital Management
San Francisco,
California
|
$34.9M
|
–
|
–
|
–
|
|
|
24
|
UBS Group
Zurich,
Switzerland
|
$33.5M
|
+$8.73M
|
+37,038
|
+42%
|
|
|
25
|
Polar Capital Holdings
London,
United Kingdom
|
$33.4M
|
+$29.5M
|
+125,205
|
New
|
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