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Madrigal Pharmaceuticals

387 hedge funds and large institutions have $13.7B invested in Madrigal Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 85 funds opening new positions, 137 increasing their positions, 113 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed

107% more first-time investments, than exits

New positions opened: 85 | Existing positions closed: 41

28% more capital invested

Capital invested by funds: $10.7B → $13.7B (+$2.99B)

21% more repeat investments, than reductions

Existing positions increased: 137 | Existing positions reduced: 113

19% more call options, than puts

Call options by funds: $323M | Put options by funds: $271M

10% more funds holding

Funds holding: 352387 (+35)

1.57% less ownership

Funds ownership: 105.34%103.78% (-1.6%)

7% less funds holding in top 10

Funds holding in top 10: 1413 (-1)

Holders
387
Holders Change
+35
Holders Change %
+9.94%
% of All Funds
4.71%
Holding in Top 10
13
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-7.14%
% of All Funds
0.16%
New
85
Increased
137
Reduced
113
Closed
41
Calls
$323M
Puts
$271M
Net Calls
+$52.6M
Net Calls Change
-$16.2M
Name Holding Trade Value Shares
Change
Change in
Stake
Carson Wealth (CWM LLC)
201
Carson Wealth (CWM LLC)
Nebraska
$1.09M -$248K -485 -21%
SFCM
202
Seven Fleet Capital Management
California
$1.08M +$950K +1,860 New
MML Investors Services
203
MML Investors Services
Massachusetts
$971K +$142K +278 +20%
Canada Life
204
Canada Life
Manitoba, Canada
$937K
KAS
205
Kestra Advisory Services
Texas
$920K +$6.64K +13 +0.8%
NIM
206
NEOS Investment Management
Connecticut
$915K -$25.5K -50 -3%
TE
207
Tema ETFs
New York
$915K -$25.5K -50 -3%
JSSH
208
J. Safra Sarasin Holding
$900K -$435K -851 -36%
AIP
209
Ameritas Investment Partners
Nebraska
$894K -$9.19K -18 -1%
AG
210
AlTi Global
New York
$869K +$511 +1 +0.1%
X
211
Xponance
Pennsylvania
$852K +$1.53K +3 +0.2%
Wealth Enhancement Advisory Services
212
Wealth Enhancement Advisory Services
Minnesota
$844K +$411K +805 +114%
Cerity Partners
213
Cerity Partners
New York
$841K +$246K +481 +50%
Public Employees Retirement Association of Colorado
214
Public Employees Retirement Association of Colorado
Colorado
$834K
NYLIM
215
New York Life Investment Management
New York
$807K -$114K -224 -14%
SA
216
Sanctuary Advisors
Indiana
$798K -$48K -94 -6%
TSS
217
Two Sigma Securities
New York
$778K +$682K +1,336 New
OAM
218
Oppenheimer Asset Management
New York
$765K +$106K +207 +19%
OSAM
219
O'Shaughnessy Asset Management
Connecticut
$747K +$218K +427 +50%
VPIM
220
Vanguard Personalized Indexing Management
California
$727K +$81.7K +160 +15%
FDCDDQ
221
Federation des caisses Desjardins du Quebec
Quebec, Canada
$726K +$82.7K +162 +15%
CWM
222
CIBC World Markets
New York
$717K +$629K +1,231 New
BMSSC
223
B. Metzler seel. Sohn & Co
Germany
$711K
Cambridge Investment Research Advisors
224
Cambridge Investment Research Advisors
Iowa
$698K -$37.3K -73 -6%
VIA
225
Virtus Investment Advisers
Connecticut
$695K -$154K -301 -20%