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Madrigal Pharmaceuticals

384 hedge funds and large institutions have $13.7B invested in Madrigal Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 83 funds opening new positions, 136 increasing their positions, 113 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
384
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
13
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$323M
Puts
$271M
Net Calls
Net Calls Change

Top Buyers

1 +$87.7M
2 +$79M
3 +$74.4M
4
Lord, Abbett & Co
Lord, Abbett & Co
New Jersey
+$72.9M
5
Alkeon Capital Management
Alkeon Capital Management
New York
+$61.3M

Top Sellers

1 -$132M
2 -$102M
3 -$58.6M
4
Morgan Stanley
Morgan Stanley
New York
-$50.7M
5
AAA
Affinity Asset Advisors
New York
-$42.8M
Name Holding Trade Value Shares
Change
Change in
Stake
SFCML
201
Seven Fleet Capital Management LP
California
$1.08M
MML Investors Services
202
MML Investors Services
Massachusetts
$971K
Canada Life
203
Canada Life
Manitoba, Canada
$937K
KAS
204
Kestra Advisory Services
Texas
$920K
NIM
205
NEOS Investment Management
Connecticut
$915K
TE
206
Tema ETFs
New York
$915K
JSSH
207
J. Safra Sarasin Holding
$900K
AIP
208
Ameritas Investment Partners
Nebraska
$894K
AG
209
AlTi Global
New York
$869K
X
210
Xponance
Pennsylvania
$852K
Wealth Enhancement Advisory Services
211
Wealth Enhancement Advisory Services
Minnesota
$844K
Cerity Partners
212
Cerity Partners
New York
$841K
Public Employees Retirement Association of Colorado
213
Public Employees Retirement Association of Colorado
Colorado
$834K
NYLIM
214
New York Life Investment Management
New York
$807K
SA
215
Sanctuary Advisors
Indiana
$798K
TSS
216
Two Sigma Securities
New York
$778K
OAM
217
Oppenheimer Asset Management
New York
$765K
OSAM
218
O'Shaughnessy Asset Management
Connecticut
$747K
VPIM
219
Vanguard Personalized Indexing Management
California
$727K
FDCDDQ
220
Federation des caisses Desjardins du Quebec
Quebec, Canada
$726K
CWM
221
CIBC World Markets
New York
$717K
BMSSC
222
B. Metzler seel. Sohn & Co
Germany
$711K
Cambridge Investment Research Advisors
223
Cambridge Investment Research Advisors
Iowa
$698K
VIA
224
Virtus Investment Advisers
Connecticut
$695K
HighTower Advisors
225
HighTower Advisors
Illinois
$683K