Two Sigma Securities’s Madrigal Pharmaceuticals MDGL Stock Holding History

Two Sigma Securities’s Portfolio MDGL Stock Details MDGL Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	$1.19M	Buy	+2,219	New	+$1.14M	0.1%	233
2026 Q1	–	Sell	-1,336	Closed	-$778K	–	1973
2025 Q4	$778K	Buy	+1,336	New	+$682K	0.11%	243
2024 Q3	–	Sell	-862	Closed	-$241K	–	3333
2024 Q2	$241K	Buy	+862	New	+$205K	﹤0.01%	2195
2016 Q2	–	Sell	-1,030	Closed	-$9K	–	482
2016 Q1	$9K	Buy	+1,030	New	+$8.6K	0.01%	261
2015 Q2	–	Sell	-335	Closed	-$23K	–	230
2015 Q1	$23K	Buy	+335	New	+$28.7K	0.02%	173

Other funds holding MDGL

BBA

Baker Bros. Advisors New York $20B AUM 154.41% 1-Year Est. Return

RTW Investments New York $11.7B AUM 174.13% 1-Year Est. Return

Jupiter Topco New York $245B AUM

ACA

Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return

Paulson & Co New York $2.58B AUM 68.51% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM

Wellington Management Group Boston, Massachusetts $580B AUM 38.23% 1-Year Est. Return

Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM

State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return

Two Sigma Securities's MDGL Position: Q2 2026 in Review

Two Sigma Securities opened a new position in Madrigal Pharmaceuticals (MDGL) in Q2 2026: 2,219 shares worth $1.19M. The stake represents 0.1% of the portfolio and ranks #233 among its holdings. This is a return to the name: Two Sigma Securities previously reported a position in MDGL as recently as Q4 2025.

Two Sigma Securities first reported a position in MDGL in Q1 2015 and has held it in 5 quarters since. 414 funds tracked by Wall St. Rank hold MDGL as of Q2 2026.

Two Sigma Securities held 2,219 shares of Madrigal Pharmaceuticals worth $1.19M as of Q2 2026.
Madrigal Pharmaceuticals was a new Two Sigma Securities position in Q2 2026.
Madrigal Pharmaceuticals made up 0.1% of Two Sigma Securities's portfolio in Q2 2026, its #233 holding.
Two Sigma Securities first reported a position in Madrigal Pharmaceuticals in Q1 2015 and has held it in 5 quarters since.
414 funds tracked by Wall St. Rank held Madrigal Pharmaceuticals as of Q2 2026.

Based on Two Sigma Securities's 13F filing for Q2 2026, filed 14 Aug 2026.