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Madrigal Pharmaceuticals

385 hedge funds and large institutions have $13.7B invested in Madrigal Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 83 funds opening new positions, 137 increasing their positions, 113 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
385
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
13
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$323M
Puts
$271M
Net Calls
Net Calls Change

Top Buyers

1 +$87.7M
2 +$79M
3 +$74.4M
4
Lord, Abbett & Co
Lord, Abbett & Co
New Jersey
+$72.9M
5
Alkeon Capital Management
Alkeon Capital Management
New York
+$61.3M

Top Sellers

1 -$132M
2 -$102M
3 -$58.6M
4
Morgan Stanley
Morgan Stanley
New York
-$50.7M
5
AAA
Affinity Asset Advisors
New York
-$42.8M
Name Holding Trade Value Shares
Change
Change in
Stake
DFCM
401
Dark Forest Capital Management
Puerto Rico
BFM
402
Boothbay Fund Management
New York
GIA
403
Gladstone Institutional Advisory
Florida
PCM
404
Penserra Capital Management
California
P
405
Pitcairn
Pennsylvania
TCA
406
Transcend Capital Advisors
New Jersey
SRL
407
Scientech Research LLC
New Jersey
QIM
408
Quantitative Investment Management
Virginia
I
409
InceptionR
California
PWM
410
Palumbo Wealth Management
New York
CCM
411
Coldstream Capital Management
Washington
BWCS
412
Beirne Wealth Consulting Services
Connecticut
SA
413
Sovran Advisors
California
BCM
414
Bayesian Capital Management
New York
JFGIW
415
Johnson Financial Group Inc (Wisconsin)
Wisconsin
SWM
416
Spire Wealth Management
Virginia
MG
417
Mather Group
Illinois
PS
418
Principal Securities
Iowa
NA
419
NewEdge Advisors
Louisiana
RA
420
Rise Advisors
New York
CI Investments Inc
421
CI Investments Inc
Ontario, Canada
FIA
422
FNY Investment Advisers
New York
JWM
423
JPL Wealth Management
Colorado
TIM
424
Tortoise Investment Management
New York
TFA
425
Transamerica Financial Advisors
Florida