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Madrigal Pharmaceuticals

387 hedge funds and large institutions have $13.7B invested in Madrigal Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 85 funds opening new positions, 137 increasing their positions, 113 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed

107% more first-time investments, than exits

New positions opened: 85 | Existing positions closed: 41

28% more capital invested

Capital invested by funds: $10.7B → $13.7B (+$2.99B)

21% more repeat investments, than reductions

Existing positions increased: 137 | Existing positions reduced: 113

19% more call options, than puts

Call options by funds: $323M | Put options by funds: $271M

10% more funds holding

Funds holding: 352387 (+35)

1.57% less ownership

Funds ownership: 105.34%103.78% (-1.6%)

7% less funds holding in top 10

Funds holding in top 10: 1413 (-1)

Holders
387
Holders Change
+35
Holders Change %
+9.94%
% of All Funds
4.71%
Holding in Top 10
13
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-7.14%
% of All Funds
0.16%
New
85
Increased
137
Reduced
113
Closed
41
Calls
$323M
Puts
$271M
Net Calls
+$52.6M
Net Calls Change
-$16.2M
Name Holding Trade Value Shares
Change
Change in
Stake
CJ
376
Caitlin John
Michigan
$1.17K
SC
377
SouthState Corp
Florida
$1.17K
HFS
378
Hughes Financial Services
Virginia
$1.17K +$1.02K +2 New
CI
379
CX Institutional
Indiana
$1K +$1.02K +2 New
MAM
380
Marquette Asset Management
Minnesota
$583 -$1.02K -2 -67%
RIAS
381
Rachor Investment Advisory Services
Michigan
$583 +$511 +1 New
SIC
382
SJS Investment Consulting
Ohio
$583 +$511 +1 New
BWL
383
Bogart Wealth LLC
Virginia
$582
FFO
384
Fortitude Family Office
Arizona
$582
TCM
385
TD Capital Management
Tennessee
$582
MI
386
Motiv8 Investments
Florida
$6 +$5.11K +10 New
Balyasny Asset Management
387
Balyasny Asset Management
Illinois
-$42.1M -82,401 Closed
EC
388
EcoR1 Capital
California
-$34.4M -75,000 Closed
ITP
389
Iron Triangle Partners
Connecticut
-$26.8M -58,378 Closed
ABG
390
Ally Bridge Group
New York
-$15M -32,662 Closed
Macquarie Group
391
Macquarie Group
Australia
-$6.19M -13,493 Closed
UOWF
392
University of Wisconsin Foundation
Wisconsin
-$5.97M -13,007 Closed
Qube Research & Technologies (QRT)
393
Qube Research & Technologies (QRT)
United Kingdom
-$1.19M -2,588 Closed
FNT
394
First National Trust
Pennsylvania
-$1.14M -2,476 Closed
FRM
395
Fox Run Management
Connecticut
-$1.06M -2,318 Closed
TI
396
Tidal Investments
Wisconsin
-$1.01M -2,209 Closed
SPC
397
Sigma Planning Corp
Michigan
-$917K -2,000 Closed
GCP
398
GSA Capital Partners
United Kingdom
-$798K -1,739 Closed
RS
399
R Squared
Hong Kong
-$743K -1,619 Closed
NSEDCP
400
NJ State Employees Deferred Compensation Plan
New Jersey
-$688K -1,500 Closed