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Kymera Therapeutics

254 hedge funds and large institutions have $6.99B invested in Kymera Therapeutics in 2025 Q4 according to their latest regulatory filings, with 68 funds opening new positions, 97 increasing their positions, 64 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed

325% more first-time investments, than exits

New positions opened: 68 | Existing positions closed: 16

53% more capital invested

Capital invested by funds: $4.58B → $6.99B (+$2.41B)

52% more repeat investments, than reductions

Existing positions increased: 97 | Existing positions reduced: 64

21% more funds holding

Funds holding: 210254 (+44)

11.78% more ownership

Funds ownership: 113.1%124.88% (+12%)

8% more funds holding in top 10

Funds holding in top 10: 1213 (+1)

41% less call options, than puts

Call options by funds: $9.18M | Put options by funds: $15.6M

Holders
254
Holders Change
+44
Holders Change %
+20.95%
% of All Funds
3.09%
Holding in Top 10
13
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+8.33%
% of All Funds
0.16%
New
68
Increased
97
Reduced
64
Closed
16
Calls
$9.18M
Puts
$15.6M
Net Calls
-$6.45M
Net Calls Change
-$12M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$695M +$206M +3,048,963 +52%
BBA
2
Baker Bros. Advisors
New York
$674M +$135M +2,005,813 +30%
ACA
3
Avoro Capital Advisors
New York
$582M +$76M +1,124,747 +18%
Vanguard Group
4
Vanguard Group
Pennsylvania
$488M +$57.1M +845,922 +16%
T. Rowe Price Associates
5
T. Rowe Price Associates
Maryland
$479M +$71.7M +1,061,957 +21%
BI
6
BVF Inc
California
$428M
BlackRock
7
BlackRock
New York
$389M +$43.1M +638,647 +15%
AVLSA
8
Atlas Venture Life Science Advisors
Massachusetts
$363M -$16M -236,588 -5%
Wellington Management Group
9
Wellington Management Group
Massachusetts
$343M -$52.9M -782,758 -15%
SL
10
Siren LLC
Connecticut
$256M -$9.54M -141,320 -4%
State Street
11
State Street
Massachusetts
$172M +$12.9M +190,383 +9%
Capital Research Global Investors
12
Capital Research Global Investors
California
$121M +$20.2M +298,609 +24%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$110M +$9.5M +140,623 +11%
DCM
14
Driehaus Capital Management
Illinois
$83.2M +$8.79M +130,144 +14%
AllianceBernstein
15
AllianceBernstein
Tennessee
$74.1M +$61M +903,296 +1,852%
UBS AM
16
UBS AM
Illinois
$71M +$3.29M +48,736 +6%
MC
17
Merck & Co
New Jersey
$60.1M
Federated Hermes
18
Federated Hermes
Pennsylvania
$59.4M +$13.9M +205,220 +37%
Holocene Advisors
19
Holocene Advisors
New York
$59.2M -$5.34M -79,124 -9%
CC
20
Commodore Capital
New York
$58.4M
Goldman Sachs
21
Goldman Sachs
New York
$57.6M +$1.95M +28,862 +4%
UBS Group
22
UBS Group
Switzerland
$57.3M +$5.96M +88,314 +14%
FCM
23
Frontier Capital Management
Massachusetts
$49.5M +$7.96M +117,900 +23%
T. Rowe Price Investment Management
24
T. Rowe Price Investment Management
Maryland
$49M +$1.25M +18,524 +3%
EAM
25
Eventide Asset Management
Massachusetts
$48.7M -$1.23M -18,160 -3%