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Kymera Therapeutics

210 hedge funds and large institutions have $4.58B invested in Kymera Therapeutics in 2025 Q3 according to their latest regulatory filings, with 40 funds opening new positions, 81 increasing their positions, 54 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

167% more call options, than puts

Call options by funds: $8.81M | Put options by funds: $3.3M

50% more repeat investments, than reductions

Existing positions increased: 81 | Existing positions reduced: 54

33% more capital invested

Capital invested by funds: $3.44B → $4.58B (+$1.14B)

5% more first-time investments, than exits

New positions opened: 40 | Existing positions closed: 38

0% more funds holding

Funds holding: 210210 (0)

8% less funds holding in top 10

Funds holding in top 10: 1312 (-1)

7.91% less ownership

Funds ownership: 121.01%113.1% (-7.9%)

Holders
210
Holders Change
Holders Change %
0%
% of All Funds
2.76%
Holding in Top 10
12
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-7.69%
% of All Funds
0.16%
New
40
Increased
81
Reduced
54
Closed
38
Calls
$8.81M
Puts
$3.3M
Net Calls
+$5.51M
Net Calls Change
-$1.42M
Name Holding Trade Value Shares
Change
Change in
Stake
BBA
1
Baker Bros. Advisors
New York
$376M
ACA
2
Avoro Capital Advisors
New York
$359M -$9.27M -205,555 -3%
Fidelity Investments
3
Fidelity Investments
Massachusetts
$333M +$20.2M +447,617 +8%
BI
4
BVF Inc
California
$311M
Vanguard Group
5
Vanguard Group
Pennsylvania
$307M -$8.94M -198,126 -4%
Wellington Management Group
6
Wellington Management Group
Massachusetts
$294M -$7.95M -176,370 -3%
T. Rowe Price Associates
7
T. Rowe Price Associates
Maryland
$289M -$79.5M -1,761,824 -26%
AVLSA
8
Atlas Venture Life Science Advisors
Massachusetts
$277M
BlackRock
9
BlackRock
New York
$247M +$9.8M +217,188 +5%
SL
10
Siren LLC
Connecticut
$194M
State Street
11
State Street
Massachusetts
$114M +$21M +465,023 +30%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$72.3M +$3.77M +83,654 +7%
Capital Research Global Investors
13
Capital Research Global Investors
California
$71.4M
Jennison Associates
14
Jennison Associates
New York
$58.2M +$9.14M +202,714 +25%
DCM
15
Driehaus Capital Management
Illinois
$53.2M +$235K +5,204 +0.6%
UBS AM
16
UBS AM
Illinois
$48.9M +$2.02M +44,835 +5%
Holocene Advisors
17
Holocene Advisors
New York
$47.6M +$37.9M +840,333 New
MC
18
Merck & Co
New Jersey
$43.7M
CC
19
Commodore Capital
New York
$42.5M
Dimensional Fund Advisors
20
Dimensional Fund Advisors
Texas
$41.4M +$7.58M +168,055 +30%
Goldman Sachs
21
Goldman Sachs
New York
$40.3M +$19.5M +432,708 +155%
UBS Group
22
UBS Group
Switzerland
$36.7M +$4.1M +90,984 +16%
EAM
23
Eventide Asset Management
Massachusetts
$36.5M +$3.68M +81,600 +14%
Alyeska Investment Group
24
Alyeska Investment Group
Illinois
$34.8M +$25.5M +565,091 +1,130%
T. Rowe Price Investment Management
25
T. Rowe Price Investment Management
Maryland
$34.6M +$23.5M +520,593 +574%

KYMR Hedge Fund Activity: Q3 2025 in Review

210 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Kymera Therapeutics (KYMR) for Q3 2025, worth a combined $4.58B — up 33% from $3.44B a quarter earlier.

Buyers outnumbered sellers: 40 funds opened new KYMR positions and 38 closed out — a net gain of 2 holders — while 81 added to existing stakes and 54 trimmed.

The largest buyer was Holocene Advisors, opening a new position worth an estimated $37.9M. The largest seller was T. Rowe Price Associates, cutting an estimated $79.5M.

  • 210 institutional investors held Kymera Therapeutics (KYMR) as of Q3 2025, unchanged from Q2 2025.
  • Funds reported $4.58B of Kymera Therapeutics stock for Q3 2025, up 33% quarter-over-quarter.
  • 40 funds opened new Kymera Therapeutics positions in Q3 2025 and 38 closed out, a net change of +2 holders.
  • The largest Kymera Therapeutics buyer in Q3 2025 was Holocene Advisors, an estimated $37.9M added.
  • The largest Kymera Therapeutics seller in Q3 2025 was T. Rowe Price Associates, an estimated $79.5M sold.

Based on aggregated 13F filings for Q3 2025.