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Kymera Therapeutics

210 hedge funds and large institutions have $3.44B invested in Kymera Therapeutics in 2025 Q2 according to their latest regulatory filings, with 64 funds opening new positions, 69 increasing their positions, 52 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

219% more call options, than puts

Call options by funds: $10.1M | Put options by funds: $3.16M

146% more first-time investments, than exits

New positions opened: 64 | Existing positions closed: 26

72% more capital invested

Capital invested by funds: $2B → $3.44B (+$1.44B)

44% more funds holding in top 10

Funds holding in top 10: 913 (+4)

33% more repeat investments, than reductions

Existing positions increased: 69 | Existing positions reduced: 52

21% more funds holding

Funds holding: 173210 (+37)

8.82% more ownership

Funds ownership: 112.19%121.01% (+8.8%)

Holders
210
Holders Change
+37
Holders Change %
+21.39%
% of All Funds
2.76%
Holding in Top 10
13
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+44.44%
% of All Funds
0.17%
New
64
Increased
69
Reduced
52
Closed
26
Calls
$10.1M
Puts
$3.16M
Net Calls
+$6.93M
Net Calls Change
+$5.69M
Name Holding Trade Value Shares
Change
Change in
Stake
T. Rowe Price Associates
1
T. Rowe Price Associates
Maryland
$299M +$5.4M +156,752 +2%
BBA
2
Baker Bros. Advisors
New York
$290M +$22.6M +655,500 +11%
ACA
3
Avoro Capital Advisors
New York
$286M +$3.29M +95,555 +1%
Vanguard Group
4
Vanguard Group
Pennsylvania
$245M +$13.4M +388,456 +7%
BI
5
BVF Inc
California
$240M +$11.7M +340,909 +7%
Fidelity Investments
6
Fidelity Investments
Massachusetts
$237M +$35.2M +1,022,760 +23%
Wellington Management Group
7
Wellington Management Group
Massachusetts
$234M -$21.5M -624,812 -10%
AVLSA
8
Atlas Venture Life Science Advisors
Massachusetts
$214M
BlackRock
9
BlackRock
New York
$181M -$4.64M -134,643 -3%
SL
10
Siren LLC
Connecticut
$150M +$6.47M +187,837 +6%
State Street
11
State Street
Massachusetts
$67.8M -$7.1M -206,276 -12%
Capital Research Global Investors
12
Capital Research Global Investors
California
$55.1M +$30.9M +896,992 +246%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$52.1M +$2.04M +59,347 +5%
DCM
14
Driehaus Capital Management
Illinois
$40.8M -$8.09M -234,901 -20%
Jennison Associates
15
Jennison Associates
New York
$36M +$9.39M +272,739 +49%
UBS AM
16
UBS AM
Illinois
$35.7M -$2.67M -77,477 -9%
RG
17
Redmile Group
California
$35.1M -$6.2M -180,124 -18%
MC
18
Merck & Co
New Jersey
$33.7M
CC
19
Commodore Capital
New York
$32.7M +$25.8M +750,000 New
DM
20
Deerfield Management
New York
$28.5M +$2.07M +60,000 +10%
Dimensional Fund Advisors
21
Dimensional Fund Advisors
Texas
$24.6M +$5.78M +167,897 +42%
EAM
22
Eventide Asset Management
Massachusetts
$24.6M +$1.3M +37,852 +7%
UBS Group
23
UBS Group
Switzerland
$24.3M -$1.24M -35,872 -6%
Citadel Advisors
24
Citadel Advisors
Florida
$22.6M +$17.8M +516,382 +20,614%
WP
25
Woodline Partners
California
$21.7M -$934K -27,134 -5%

KYMR Hedge Fund Activity: Q2 2025 in Review

210 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Kymera Therapeutics (KYMR) for Q2 2025, worth a combined $3.44B — up 72% from $2B a quarter earlier.

Buyers outnumbered sellers: 64 funds opened new KYMR positions and 26 closed out — a net gain of 38 holders — while 69 added to existing stakes and 52 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $35.2M. The largest seller was Janus Henderson Group, cutting an estimated $25.9M.

  • 210 institutional investors held Kymera Therapeutics (KYMR) as of Q2 2025, up from 173 in Q1 2025.
  • Funds reported $3.44B of Kymera Therapeutics stock for Q2 2025, up 72% quarter-over-quarter.
  • 64 funds opened new Kymera Therapeutics positions in Q2 2025 and 26 closed out, a net change of +38 holders.
  • The largest Kymera Therapeutics buyer in Q2 2025 was Fidelity Investments, an estimated $35.2M added.
  • The largest Kymera Therapeutics seller in Q2 2025 was Janus Henderson Group, an estimated $25.9M sold.

Based on aggregated 13F filings for Q2 2025.