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Krystal Biotech

332 hedge funds and large institutions have $7.01B invested in Krystal Biotech in 2025 Q4 according to their latest regulatory filings, with 81 funds opening new positions, 111 increasing their positions, 105 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more call options, than puts

Call options by funds: $ | Put options by funds: $

more capital invested

Capital invested by funds: $ → $

more funds holding

Funds holding:

14% more funds holding in top 10

Funds holding in top 10: 78 (+1)

1.26% more ownership

Funds ownership: 96.77%98.03% (+1.3%)

6% more repeat investments, than reductions

Existing positions increased: 111 | Existing positions reduced: 105

Holders
332
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
8
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$53M
Puts
$21.6M
Net Calls
Net Calls Change

Top Buyers

1 +$86.1M
2 +$47.8M
3 +$44.1M
4
ACA
Avoro Capital Advisors
New York
+$23.4M
5
Franklin Resources
Franklin Resources
California
+$22.3M

Top Sellers

1 -$67M
2 -$52.7M
3 -$42.1M
4
UBS AM
UBS AM
Illinois
-$35.6M
5
Millennium Management
Millennium Management
New York
-$28.2M
Name Holding Trade Value Shares
Change
Change in
Stake
FHA
326
Flagship Harbor Advisors
Massachusetts
$493
SEP
327
Signature Equity Partners
Ohio
$493
RS
328
Rakuten Securities
Japan
$247
AWM
329
Abound Wealth Management
Tennessee
$247
RWM
330
Rialto Wealth Management
New York
$247
Optiver Holding
331
Optiver Holding
Netherlands
$247
KG
332
Kilter Group
New York
$247
RAM
333
Readystate Asset Management
Illinois
FCM
334
Fieldview Capital Management
Michigan
AA
335
ALPS Advisors
Colorado
ACP
336
Acuta Capital Partners
California
Schroder Investment Management Group
337
Schroder Investment Management Group
United Kingdom
Connor, Clark & Lunn Investment Management (CC&L)
338
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
STA
339
Summit Trail Advisors
New York
DFCM
340
Dark Forest Capital Management
Puerto Rico
OAC
341
OMERS Administration Corp
Ontario, Canada
CP
342
CenterBook Partners
Connecticut
Jane Street
343
Jane Street
New York
SB
344
SIG Brokerage
New York
AACP
345
Advantage Alpha Capital Partners
California
Man Group
346
Man Group
United Kingdom
FGP
347
Freestone Grove Partners
California
LJAC
348
L.J. Altfest & Co
New York
CCIA
349
Campbell & Co Investment Adviser
Maryland
ASN
350
Advisory Services Network
Georgia