|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$433M
|
+$43.5M
|
+515,063
|
+10%
|
|
|
2
|
|
$181M
|
+$21.6M
|
+255,697
|
+13%
|
|
|
3
|
RA Capital Management
Boston,
Massachusetts
|
$157M
|
+$33.7M
|
+399,026
|
+25%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$140M
|
+$27M
|
+319,621
|
+22%
|
|
|
5
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$135M
|
+$31.4M
|
+371,576
|
+28%
|
|
|
6
|
|
$126M
|
+$70M
|
+828,248
|
+110%
|
|
|
7
|
Wellington Management Group
Boston,
Massachusetts
|
$121M
|
+$9.14M
|
+108,197
|
+8%
|
|
|
8
|
Atlas Venture Life Science Advisors
Cambridge,
Massachusetts
|
$120M
|
-$53.1M
|
-628,742
|
-29%
|
|
|
9
|
Frazier Life Sciences Management
Palo Alto,
California
|
$100M
|
-$15.1M
|
-178,534
|
-12%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$94.3M
|
+$12M
|
+142,394
|
+14%
|
|
|
11
|
|
$84.8M
|
-$29.4M
|
-347,470
|
-25%
|
|
|
12
|
Siren LLC
Greenwich,
Connecticut
|
$78.5M
|
+$6.34M
|
+75,000
|
+8%
|
|
|
13
|
Woodline Partners
San Francisco,
California
|
$76.1M
|
+$7.68M
|
+90,878
|
+10%
|
|
|
14
|
|
$59.9M
|
+$19M
|
+225,114
|
+43%
|
|
|
15
|
Vestal Point Capital
New York
|
$58.4M
|
+$19.9M
|
+235,000
|
+47%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$54.4M
|
+$4.8M
|
+56,807
|
+9%
|
|
|
17
|
BVF Inc
San Francisco,
California
|
$51.6M
|
+$54.9M
|
+650,000
|
New
|
|
|
18
|
Jennison Associates
New York
|
$42.3M
|
+$45M
|
+532,079
|
New
|
|
|
19
|
First Light Asset Management
Edina,
Minnesota
|
$41.5M
|
+$24.7M
|
+291,981
|
+126%
|
|
|
20
|
Deerfield Management
New York
|
$40.6M
|
-$34.5M
|
-408,240
|
-44%
|
|
|
21
|
Logos Global Management
San Francisco,
California
|
$40.5M
|
+$5.07M
|
+60,000
|
+13%
|
|
|
22
|
Armistice Capital
New York
|
$39.7M
|
+$5.36M
|
+63,391
|
+15%
|
|
|
23
|
Checkpoint Capital
San Francisco,
California
|
$36M
|
+$1.94M
|
+22,992
|
+5%
|
|
|
24
|
Perceptive Advisors
New York
|
$35.8M
|
+$38.1M
|
+450,743
|
New
|
|
|
25
|
Eventide Asset Management
Boston,
Massachusetts
|
$31.4M
|
+$7.38M
|
+87,349
|
+28%
|
|
