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Disc Medicine
IRON

Name Holding Trade Value Shares
Change 		Change in
Stake
O
1
OrbiMed
New York
$78.9M +$86.6M +194,207 New
Fidelity Investments
2
Fidelity Investments
Massachusetts
$36.1M +$41.5M +92,983 New
FCMV
3
Foresite Capital Management V
California
$33M +$36.2M +81,171 New
Vanguard Group
4
Vanguard Group
Pennsylvania
$25M +$27.5M +61,605 New
Wellington Management Group
5
Wellington Management Group
Massachusetts
$19.7M +$22M +49,332 New
SCM
6
Suvretta Capital Management
New York
$17.8M +$19.5M +43,745 New
BC
7
Boxer Capital
California
$17.6M +$19.3M +43,333 New
Adage Capital Partners
8
Adage Capital Partners
Massachusetts
$12.2M +$13.4M +30,000 New
OM
9
Opaleye Management
Massachusetts
$11M +$12.1M +27,017 New
T. Rowe Price Associates
10
T. Rowe Price Associates
Maryland
$9.65M +$11.2M +25,000 New
IC
11
Ikarian Capital
Texas
$9.27M +$10.2M +22,813 New
Franklin Resources
12
Franklin Resources
California
$6.78M +$7.43M +16,667 New
Point72 Asset Management
13
Point72 Asset Management
Connecticut
$6.51M +$7.14M +16,017 New
CAM
14
Cormorant Asset Management
Massachusetts
$6.44M +$7.06M +15,833 New
JCM
15
JS Capital Management
New York
$6.43M +$7.05M +15,815 New
Alyeska Investment Group
16
Alyeska Investment Group
Illinois
$6.34M +$8.03M +18,004 New
Citadel Advisors
17
Citadel Advisors
Florida
$5.75M +$6.31M +14,145 New
WP
18
Woodline Partners
California
$4.58M +$5.03M +11,277 New
Millennium Management
19
Millennium Management
New York
$4.47M +$4.91M +11,001 New
Geode Capital Management
20
Geode Capital Management
Massachusetts
$3.8M +$4.17M +9,352 New
HMC
21
Harvard Management Company
Massachusetts
$3.39M +$3.72M +8,333 New
BlackRock
22
BlackRock
New York
$3.27M +$3.59M +8,043 New
ACM
23
Altium Capital Management
New York
$2.76M +$3.03M +6,800 New
ECM
24
Endurant Capital Management
California
$2.3M +$2.53M +5,663 New
DCM
25
DAFNA Capital Management
California
$2.03M +$2.23M +5,000 New
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