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Ionis Pharmaceuticals
IONS

Name Holding Trade Value Shares
Change 		Change in
Stake
VAM
26
Visium Asset Management
New York
$19M +$15M +706,804 New
SNC
27
Stifel Nicolaus & Co
Missouri
$18.1M +$14.3M +674,192 New
Bank of New York Mellon
28
Bank of New York Mellon
New York
$17.6M +$13.9M +654,705 New
TCIM
29
TIAA CREF Investment Management
New York
$14M +$11.1M +522,714 New
MG
30
Meditor Group
Bermuda
$14M +$11.1M +520,000 New
Geode Capital Management
31
Geode Capital Management
Massachusetts
$13.1M +$10.4M +487,622 New
Norges Bank
32
Norges Bank
Norway
$13M +$10.3M +483,296 New
Goldman Sachs
33
Goldman Sachs
New York
$11.8M +$9.31M +437,700 New
Charles Schwab
34
Charles Schwab
California
$11.7M +$8.75M +411,600 New
MCM
35
Montibus Capital Management
Oregon
$10.6M +$8.36M +392,962 New
OAM
36
Oxford Asset Management
United Kingdom
$9.7M +$7.67M +360,836 New
Invesco
37
Invesco
Georgia
$8.77M +$6.94M +326,422 New
WHI
38
William Harris Investors
Illinois
$8.76M +$6.93M +325,834 New
Susquehanna International Group
39
Susquehanna International Group
Pennsylvania
$8.13M +$6.43M +302,504 New
BIM
40
BlackRock Investment Management
Delaware
$7.99M +$6.32M +297,376 New
BIM
41
Bogle Investment Management
Massachusetts
$7.92M +$6.26M +294,607 New
BG
42
BlackRock Group
United Kingdom
$7.7M +$6.1M +286,683 New
EA
43
Emerald Advisers
Pennsylvania
$7.33M +$5.8M +272,927 New
Dimensional Fund Advisors
44
Dimensional Fund Advisors
Texas
$7.07M +$5.59M +263,021 New
CS
45
Credit Suisse
Switzerland
$6.71M +$5.31M +249,855 New
BBA
46
Baker Bros. Advisors
New York
$6.64M +$5.25M +247,036 New
ARTA
47
A.R.T. Advisors
New York
$5.4M +$4.27M +200,921 New
QBFM
48
QS Batterymarch Financial Management
New York
$5.32M +$4.21M +197,800 New
Deutsche Bank
49
Deutsche Bank
Germany
$5.3M +$4.19M +197,162 New
California State Teachers Retirement System (CalSTRS)
50
California State Teachers Retirement System (CalSTRS)
California
$5.26M +$4.16M +195,714 New
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