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441 hedge funds and large institutions have $15.3B invested in Insmed in 2025 Q1 according to their latest regulatory filings, with 56 funds opening new positions, 185 increasing their positions, 151 reducing their positions, and 48 closing their positions.

New
Increased
Maintained
Reduced
Closed

23% more repeat investments, than reductions

Existing positions increased: 185 | Existing positions reduced: 151

17% more first-time investments, than exits

New positions opened: 56 | Existing positions closed: 48

15% more capital invested

Capital invested by funds: $13.3B → $15.3B (+$2.01B)

7% more funds holding in top 10

Funds holding in top 10: 2931 (+2)

2.65% more ownership

Funds ownership: 107.64%110.29% (+2.7%)

1% more funds holding

Funds holding: 438441 (+3)

50% less call options, than puts

Call options by funds: $73M | Put options by funds: $145M

Holders
441
Holders Change
+3
Holders Change %
+0.68%
% of All Funds
5.91%
Holding in Top 10
31
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+6.9%
% of All Funds
0.42%
New
56
Increased
185
Reduced
151
Closed
48
Calls
$73M
Puts
$145M
Net Calls
-$72M
Net Calls Change
-$110M
Name Holding Trade Value Shares
Change
Change in
Stake
Legal & General Group
126
Legal & General Group
United Kingdom
$13.7M +$320K +4,188 +2%
Neuberger Berman Group
127
Neuberger Berman Group
New York
$13.5M +$2.1M +27,392 +18%
SBH
128
Segall Bryant & Hamill
Illinois
$13M +$2.43M +31,814 +23%
California State Teachers Retirement System (CalSTRS)
129
California State Teachers Retirement System (CalSTRS)
California
$12M +$333K +4,355 +3%
Two Sigma Advisers
130
Two Sigma Advisers
New York
$12M -$13M -169,300 -52%
Prudential Financial
131
Prudential Financial
New Jersey
$11.8M +$647K +8,455 +6%
BG
132
Bellevue Group
Switzerland
$11.5M -$8.26M -107,933 -42%
WCM Investment Management
133
WCM Investment Management
California
$11.3M -$27.6K -361 -0.2%
Rafferty Asset Management
134
Rafferty Asset Management
New York
$11.1M -$2.67M -34,929 -19%
AAA
135
Affinity Asset Advisors
New York
$10.7M +$6.88M +90,000 +180%
RAM
136
Readystate Asset Management
Illinois
$10.3M +$8.29M +108,379 +414%
SFI
137
Susquehanna Fundamental Investments
Pennsylvania
$10.1M -$10.6M -138,035 -51%
Schroder Investment Management Group
138
Schroder Investment Management Group
United Kingdom
$9.94M -$10.8M -140,568 -52%
Universal-Beteiligungs- und Servicegesellschaft
139
Universal-Beteiligungs- und Servicegesellschaft
Germany
$9.86M +$2.35M +30,727 +31%
State of Wisconsin Investment Board
140
State of Wisconsin Investment Board
Wisconsin
$9.61M +$296K +3,864 +3%
Jane Street
141
Jane Street
New York
$9.5M -$10.6M -139,134 -53%
VanEck Associates
142
VanEck Associates
New York
$9.43M +$330K +4,318 +4%
Mirae Asset Global ETFs Holdings
143
Mirae Asset Global ETFs Holdings
Hong Kong
$8.36M +$319K +4,176 +4%
APM
144
Avidity Partners Management
Texas
$8.16M -$9.62M -125,800 -54%
ACP
145
Acuta Capital Partners
California
$8.09M +$97.5K +1,274 +1%
IIM
146
INTECH Investment Management
Florida
$7.78M +$2.35M +30,752 +43%
TLP
147
Tri Locum Partners
New York
$7.77M +$7.79M +101,859 New
MIM
148
MetLife Investment Management
New Jersey
$7.65M -$246K -3,219 -3%
TCM
149
Tang Capital Management
California
$7.63M
ACM
150
Atika Capital Management
New York
$7.32M +$7.34M +96,000 New

INSM Hedge Fund Activity: Q1 2025 in Review

441 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q1 2025, worth a combined $15.3B — up 15% from $13.3B a quarter earlier.

Buyers outnumbered sellers: 56 funds opened new INSM positions and 48 closed out — a net gain of 8 holders — while 185 added to existing stakes and 151 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $235M. The largest seller was Fidelity Investments, cutting an estimated $112M.

  • 441 institutional investors held Insmed (INSM) as of Q1 2025, up from 438 in Q4 2024.
  • Funds reported $15.3B of Insmed stock for Q1 2025, up 15% quarter-over-quarter.
  • 56 funds opened new Insmed positions in Q1 2025 and 48 closed out, a net change of +8 holders.
  • The largest Insmed buyer in Q1 2025 was JP Morgan Chase, an estimated $235M added.
  • The largest Insmed seller in Q1 2025 was Fidelity Investments, an estimated $112M sold.

Based on aggregated 13F filings for Q1 2025.