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Immunome

153 hedge funds and large institutions have $1.07B invested in Immunome in 2025 Q3 according to their latest regulatory filings, with 27 funds opening new positions, 64 increasing their positions, 38 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

80% more first-time investments, than exits

New positions opened: 27 | Existing positions closed: 15

68% more repeat investments, than reductions

Existing positions increased: 64 | Existing positions reduced: 38

45% more capital invested

Capital invested by funds: $739M → $1.07B (+$331M)

33% more funds holding in top 10

Funds holding in top 10: 34 (+1)

13.7% more ownership

Funds ownership: 91.29%104.99% (+14%)

8% more funds holding

Funds holding: 142153 (+11)

90% less call options, than puts

Call options by funds: $4.89M | Put options by funds: $50.7M

Holders
153
Holders Change
+11
Holders Change %
+7.75%
% of All Funds
2.01%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.05%
New
27
Increased
64
Reduced
38
Closed
15
Calls
$4.89M
Puts
$50.7M
Net Calls
-$45.8M
Net Calls Change
-$7.34M
Name Holding Trade Value Shares
Change
Change in
Stake
GGHC
51
Gilder Gagnon Howe & Co
New York
$1.56M +$1.32M +133,112 New
PCA
52
Private Capital Advisors
Connecticut
$1.38M -$714K -71,798 -38%
UBS AM
53
UBS AM
Illinois
$1.32M -$740K -74,400 -40%
RhumbLine Advisers
54
RhumbLine Advisers
Massachusetts
$1.27M -$3.32K -334 -0.3%
BC
55
Birchview Capital
Vermont
$1.23M +$448K +45,000 +75%
Bank of America
56
Bank of America
North Carolina
$1.08M -$74.8K -7,521 -8%
Los Angeles Capital Management
57
Los Angeles Capital Management
California
$1.02M +$450K +45,245 +108%
Rafferty Asset Management
58
Rafferty Asset Management
New York
$1.01M +$100K +10,088 +13%
Legal & General Group
59
Legal & General Group
United Kingdom
$949K +$179K +18,044 +29%
Nisa Investment Advisors
60
Nisa Investment Advisors
Missouri
$942K +$778K +78,200 +3,513%
SSA
61
Schonfeld Strategic Advisors
New York
$856K +$727K +73,058 New
XT
62
XTX Topco
Cayman Islands
$826K +$701K +70,514 New
Susquehanna International Group
63
Susquehanna International Group
Pennsylvania
$822K -$647K -64,997 -48%
GCP
64
GSA Capital Partners
United Kingdom
$778K -$95.8K -9,626 -13%
California State Teachers Retirement System (CalSTRS)
65
California State Teachers Retirement System (CalSTRS)
California
$771K +$275K +27,605 +72%
American Century Companies
66
American Century Companies
Missouri
$741K +$630K +63,306 New
Simplex Trading
67
Simplex Trading
Illinois
$722K +$339K +34,094 +124%
FCH
68
Freestone Capital Holdings
Washington
$722K +$279 +28 +0%
JGC
69
J. Goldman & Co
New York
$718K +$610K +61,344 New
Royal Bank of Canada
70
Royal Bank of Canada
Ontario, Canada
$716K +$593K +59,640 +3,942%
Deutsche Bank
71
Deutsche Bank
Germany
$714K +$71.7K +7,209 +13%
Jane Street
72
Jane Street
New York
$711K +$604K +60,708 New
Lido Advisors
73
Lido Advisors
California
$691K -$338 -34 -0.1%
VRS
74
Virginia Retirement Systems
Virginia
$684K +$123K +12,400 +27%
Invesco
75
Invesco
Georgia
$656K +$271K +27,224 +95%

IMNM Hedge Fund Activity: Q3 2025 in Review

153 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Immunome (IMNM) for Q3 2025, worth a combined $1.07B — up 45% from $739M a quarter earlier.

Buyers outnumbered sellers: 27 funds opened new IMNM positions and 15 closed out — a net gain of 12 holders — while 64 added to existing stakes and 38 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $68.5M. The largest seller was Toronto Dominion Bank, cutting an estimated $10.4M.

  • 153 institutional investors held Immunome (IMNM) as of Q3 2025, up from 142 in Q2 2025.
  • Funds reported $1.07B of Immunome stock for Q3 2025, up 45% quarter-over-quarter.
  • 27 funds opened new Immunome positions in Q3 2025 and 15 closed out, a net change of +12 holders.
  • The largest Immunome buyer in Q3 2025 was Fidelity Investments, an estimated $68.5M added.
  • The largest Immunome seller in Q3 2025 was Toronto Dominion Bank, an estimated $10.4M sold.

Based on aggregated 13F filings for Q3 2025.