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Immunome

153 hedge funds and large institutions have $1.07B invested in Immunome in 2025 Q3 according to their latest regulatory filings, with 27 funds opening new positions, 64 increasing their positions, 38 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

80% more first-time investments, than exits

New positions opened: 27 | Existing positions closed: 15

68% more repeat investments, than reductions

Existing positions increased: 64 | Existing positions reduced: 38

45% more capital invested

Capital invested by funds: $739M → $1.07B (+$331M)

33% more funds holding in top 10

Funds holding in top 10: 34 (+1)

13.7% more ownership

Funds ownership: 91.29%104.99% (+14%)

8% more funds holding

Funds holding: 142153 (+11)

90% less call options, than puts

Call options by funds: $4.89M | Put options by funds: $50.7M

Holders
153
Holders Change
+11
Holders Change %
+7.75%
% of All Funds
2.01%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.05%
New
27
Increased
64
Reduced
38
Closed
15
Calls
$4.89M
Puts
$50.7M
Net Calls
-$45.8M
Net Calls Change
-$7.34M
Name Holding Trade Value Shares
Change
Change in
Stake
TD Asset Management
26
TD Asset Management
Ontario, Canada
$8.21M +$952K +95,750 +16%
DCM
27
Driehaus Capital Management
Illinois
$8.16M +$4.73M +475,551 +215%
Marshall Wace
28
Marshall Wace
United Kingdom
$8.11M -$6.02M -605,573 -47%
Charles Schwab
29
Charles Schwab
California
$7.77M +$232K +23,363 +4%
NFT
30
Nan Fung Trinity
Hong Kong
$6.93M +$430K +43,253 +8%
UBS Group
31
UBS Group
Switzerland
$6.84M +$1.57M +158,027 +37%
PBPIA
32
Pivotal bioVenture Partners Investment Advisor
California
$5.88M +$5M +502,512 New
SI
33
Sofinnova Investments
California
$5.11M -$3.41M -342,425 -44%
GIM
34
Granahan Investment Management
Massachusetts
$4.99M +$333K +33,468 +9%
PHP
35
Parkman Healthcare Partners
Connecticut
$4.11M +$3.49M +351,131 New
Dimensional Fund Advisors
36
Dimensional Fund Advisors
Texas
$3.96M +$2.32M +233,571 +223%
Manulife (Manufacturers Life Insurance)
37
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$3.4M +$95.8K +9,626 +3%
KCM
38
Kennedy Capital Management
Missouri
$3.01M +$1.47M +148,074 +135%
Wellington Management Group
39
Wellington Management Group
Massachusetts
$2.98M +$420K +42,239 +20%
Bank of New York Mellon
40
Bank of New York Mellon
New York
$2.54M +$117K +11,781 +6%
Goldman Sachs
41
Goldman Sachs
New York
$2.45M -$2.68M -269,672 -56%
Barclays
42
Barclays
United Kingdom
$2.44M -$212K -21,360 -9%
Renaissance Technologies
43
Renaissance Technologies
New York
$2.37M +$1.02M +102,928 +104%
AIM
44
AXA Investment Managers
France
$2.11M +$1.79M +180,056 New
Handelsbanken Fonder
45
Handelsbanken Fonder
Sweden
$2.11M -$199K -20,000 -10%
NIM
46
NEOS Investment Management
Connecticut
$1.9M +$465K +46,755 +41%
TE
47
Tema ETFs
New York
$1.9M +$465K +46,755 +41%
SFM
48
Sphera Funds Management
Israel
$1.72M +$1.46M +147,200 New
N
49
Nuveen
North Carolina
$1.7M -$956K -96,066 -40%
Swiss National Bank
50
Swiss National Bank
Switzerland
$1.58M +$21.9K +2,200 +2%

IMNM Hedge Fund Activity: Q3 2025 in Review

153 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Immunome (IMNM) for Q3 2025, worth a combined $1.07B — up 45% from $739M a quarter earlier.

Buyers outnumbered sellers: 27 funds opened new IMNM positions and 15 closed out — a net gain of 12 holders — while 64 added to existing stakes and 38 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $68.5M. The largest seller was Toronto Dominion Bank, cutting an estimated $10.4M.

  • 153 institutional investors held Immunome (IMNM) as of Q3 2025, up from 142 in Q2 2025.
  • Funds reported $1.07B of Immunome stock for Q3 2025, up 45% quarter-over-quarter.
  • 27 funds opened new Immunome positions in Q3 2025 and 15 closed out, a net change of +12 holders.
  • The largest Immunome buyer in Q3 2025 was Fidelity Investments, an estimated $68.5M added.
  • The largest Immunome seller in Q3 2025 was Toronto Dominion Bank, an estimated $10.4M sold.

Based on aggregated 13F filings for Q3 2025.