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Immunome
IMNM

142 hedge funds and large institutions have $518M invested in Immunome in 2025 Q1 according to their latest regulatory filings, with 39 funds opening new positions, 71 increasing their positions, 16 reducing their positions, and 17 closing their positions.

New
Increased
Maintained
Reduced
Closed

344% more repeat investments, than reductions

Existing positions increased: 71 | Existing positions reduced: 16

129% more first-time investments, than exits

New positions opened: 39 | Existing positions closed: 17

18% more funds holding

Funds holding: 120 → 142 (+22)

3.08% more ownership

Funds ownership: 85.41% → 88.49% (+3.1%)

0% more funds holding in top 10

Funds holding in top 10: 3 → 3 (0)

8% less capital invested

Capital invested by funds: $566M → $518M (-$47.9M)

98% less call options, than puts

Call options by funds: $449K | Put options by funds: $29.1M

Holders
142
Holders Change
+22
Holders Change %
+18.33%
% of All Funds
1.9%
Holding in Top 10
3
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.04%
New
39
Increased
71
Reduced
16
Closed
17
Calls
$449K
Puts
$29.1M
Net Calls
-$28.6M
Net Calls Change
-$7.17M

Top Buyers

Rank Fund Capital Flow
1
Point72 Asset Management
Point72 Asset Management
Connecticut
+$35.2M
2
Primecap Management
Primecap Management
California
+$30.1M
3
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
+$19.7M
4
BlackRock
BlackRock
New York
+$14.8M
5
OM
Opaleye Management
Massachusetts
+$14.5M

Top Sellers

Rank Fund Capital Flow
1
Janus Henderson Group
Janus Henderson Group
United Kingdom
-$13.1M
2
Renaissance Technologies
Renaissance Technologies
New York
-$1.92M
3
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
-$1.14M
4
CSS
Cubist Systematic Strategies
Connecticut
-$902K
5
Goldman Sachs
Goldman Sachs
New York
-$772K
Name Holding Trade Value Shares
Change 		Change in
Stake
DCM
26
Driehaus Capital Management
Illinois
$4.11M +$5.86M +610,551 New
TD Asset Management
27
TD Asset Management
Ontario, Canada
$4.08M +$1.76M +183,460 +43%
Millennium Management
28
Millennium Management
New York
$3.1M +$2.9M +302,631 +191%
GIM
29
Granahan Investment Management
Massachusetts
$2.82M +$1.01M +105,032 +33%
Bank of America
30
Bank of America
North Carolina
$2.32M +$2.88M +300,474 +684%
UBS Group
31
UBS Group
Switzerland
$2.32M +$1.5M +155,854 +83%
Citadel Advisors
32
Citadel Advisors
Florida
$2.29M +$2.34M +244,237 +255%
Schroder Investment Management Group
33
Schroder Investment Management Group
United Kingdom
$1.84M +$2.53M +263,867 New
Manulife (Manufacturers Life Insurance)
34
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$1.82M +$787K +82,070 +43%
EAM
35
Exome Asset Management
New York
$1.78M +$2.53M +263,841 New
N
36
Nuveen
North Carolina
$1.61M +$517K +53,853 +29%
RAM
37
Readystate Asset Management
Illinois
$1.51M +$2.15M +224,240 New
Handelsbanken Fonder
38
Handelsbanken Fonder
Sweden
$1.35M – – –
Goldman Sachs
39
Goldman Sachs
New York
$1.3M -$772K -80,459 -29%
Bank of New York Mellon
40
Bank of New York Mellon
New York
$1.3M +$671K +69,944 +57%
Axa
41
Axa
France
$1.21M -$2.17K -226 -0.1%
VCIM
42
Velan Capital Investment Management
Georgia
$1.03M +$1.47M +153,500 New
Wellington Management Group
43
Wellington Management Group
Massachusetts
$1.03M +$71.4K +7,447 +5%
Citigroup
44
Citigroup
New York
$976K +$650K +67,780 +88%
Swiss National Bank
45
Swiss National Bank
Switzerland
$861K +$495K +51,600 +68%
Barclays
46
Barclays
United Kingdom
$852K +$214K +22,265 +21%
Renaissance Technologies
47
Renaissance Technologies
New York
$781K -$1.92M -200,000 -63%
Rafferty Asset Management
48
Rafferty Asset Management
New York
$690K +$202K +21,084 +26%
ECM
49
ExodusPoint Capital Management
New York
$687K +$980K +102,153 New
ZP
50
Zimmer Partners
New York
$673K +$959K +100,000 New
1
2
3 4 5

IMNM Hedge Fund Activity: Q1 2025 in Review

142 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Immunome (IMNM) for Q1 2025, worth a combined $518M — down 8.5% from $566M a quarter earlier.

Buyers outnumbered sellers: 39 funds opened new IMNM positions and 17 closed out — a net gain of 22 holders — while 71 added to existing stakes and 16 trimmed.

The largest buyer was Point72 Asset Management, adding an estimated $35.2M. The largest seller was Janus Henderson Group, cutting an estimated $13.1M.

  • 142 institutional investors held Immunome (IMNM) as of Q1 2025, up from 120 in Q4 2024.
  • Funds reported $518M of Immunome stock for Q1 2025, down 8.5% quarter-over-quarter.
  • 39 funds opened new Immunome positions in Q1 2025 and 17 closed out, a net change of +22 holders.
  • The largest Immunome buyer in Q1 2025 was Point72 Asset Management, an estimated $35.2M added.
  • The largest Immunome seller in Q1 2025 was Janus Henderson Group, an estimated $13.1M sold.

Based on aggregated 13F filings for Q1 2025.