Fractyl Health
GUTS
99 hedge funds and large institutions have $247M invested in Fractyl Health in 2025 Q4 according to their latest regulatory filings, with 34 funds opening new positions, 32 increasing their positions, 17 reducing their positions, and 8 closing their positions.
325% more first-time investments, than exits
New positions opened: 34 | Existing positions closed: 8
125% more capital inflows, than outflows
Capital inflows: $60.7M | Capital outflows: $27M
88% more repeat investments, than reductions
Existing positions increased: 32 | Existing positions reduced: 17
32% more funds holding
Funds holding: 75 → 99 (+24)
15.28% more ownership
Funds ownership: 66.77% → 82.04% (+15%)
0% more funds holding in top 10
Funds holding in top 10: 4 → 4 (0)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Marshall Wace
London,
United Kingdom
|
+$6.69M |
| 2 |
Vanguard Group
Malvern,
Pennsylvania
|
+$6.61M |
| 3 |
Pale Fire Capital SE
Prague,
Czech Republic
|
+$5.17M |
| 4 |
Goldman Sachs
New York
|
+$4.72M |
| 5 |
Atom Investors
Austin,
Texas
|
+$3.03M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Rosalind Advisors
Toronto,
Ontario, Canada
|
-$7.43M |
| 2 |
Soleus Capital Management
Greenwich,
Connecticut
|
-$3.38M |
| 3 |
Alyeska Investment Group
Chicago,
Illinois
|
-$2.96M |
| 4 |
Point72 Asset Management
Stamford,
Connecticut
|
-$2.93M |
| 5 |
Citadel Advisors
Miami,
Florida
|
-$2.5M |
GUTS Hedge Fund Activity: Q4 2025 in Review
99 of the 8,306 institutional investors tracked by Wall St. Rank reported a position in Fractyl Health (GUTS) for Q4 2025, worth a combined $247M — up 70% from $145M a quarter earlier.
Buyers outnumbered sellers: 34 funds opened new GUTS positions and 8 closed out — a net gain of 26 holders — while 32 added to existing stakes and 17 trimmed.
The largest buyer was Marshall Wace, adding an estimated $6.69M. The largest seller was Rosalind Advisors, cutting an estimated $7.43M.
- 99 institutional investors held Fractyl Health (GUTS) as of Q4 2025, up from 75 in Q3 2025.
- Funds reported $247M of Fractyl Health stock for Q4 2025, up 70% quarter-over-quarter.
- 34 funds opened new Fractyl Health positions in Q4 2025 and 8 closed out, a net change of +26 holders.
- The largest Fractyl Health buyer in Q4 2025 was Marshall Wace, an estimated $6.69M added.
- The largest Fractyl Health seller in Q4 2025 was Rosalind Advisors, an estimated $7.43M sold.
Based on aggregated 13F filings for Q4 2025.