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Fractyl Health
GUTS

62 hedge funds and large institutions have $44.9M invested in Fractyl Health in 2025 Q2 according to their latest regulatory filings, with 19 funds opening new positions, 14 increasing their positions, 20 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

51% more capital invested

Capital invested by funds: $29.7M → $44.9M (+$15.2M)

33% more funds holding in top 10

Funds holding in top 10: 3 → 4 (+1)

5.55% more ownership

Funds ownership: 50.99% → 56.54% (+5.5%)

5% less funds holding

Funds holding: 65 → 62 (-3)

14% less first-time investments, than exits

New positions opened: 19 | Existing positions closed: 22

30% less repeat investments, than reductions

Existing positions increased: 14 | Existing positions reduced: 20

Holders
62
Holders Change
-3
Holders Change %
-4.62%
% of All Funds
0.82%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.05%
New
19
Increased
14
Reduced
20
Closed
22
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
GCGM
General Catalyst Group Management
Massachusetts
+$7.89M
2
Millennium Management
Millennium Management
New York
+$827K
3
YIH
Y-Intercept (HK)
Hong Kong
+$180K
4
WP
Woodline Partners
California
+$131K
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
+$129K

Top Sellers

Rank Fund Capital Flow
1
BlackRock
BlackRock
New York
-$2.54M
2
Geode Capital Management
Geode Capital Management
Massachusetts
-$654K
3
Vanguard Group
Vanguard Group
Pennsylvania
-$309K
4
Northern Trust
Northern Trust
Illinois
-$289K
5
State Street
State Street
Massachusetts
-$197K
Name Holding Trade Value Shares
Change 		Change in
Stake
GCGM
1
General Catalyst Group Management
Massachusetts
$7.91M +$7.89M +4,884,193 New
DMC
2
Deer Management Company
New York
$7.73M – – –
HM
3
HCC Manager
Illinois
$7.57M – – –
MC
4
Maverick Capital
Texas
$6.88M – – –
MCM
5
M28 Capital Management
Connecticut
$3.01M – – –
Vanguard Group
6
Vanguard Group
Pennsylvania
$1.8M -$309K -191,096 -15%
Massachusetts Financial Services
7
Massachusetts Financial Services
Massachusetts
$1.51M -$50.8K -31,471 -3%
BlackRock
8
BlackRock
New York
$1.44M -$2.54M -1,569,187 -64%
AI
9
Alphabet Inc
California
$1.07M – – –
6CM
10
683 Capital Management
New York
$1.04M -$8.08K -5,000 -0.8%
WP
11
Woodline Partners
California
$969K +$131K +80,920 +16%
Millennium Management
12
Millennium Management
New York
$847K +$827K +511,825 +4,591%
CCM
13
Catalio Capital Management
New York
$347K – – –
SCM
14
Silverarc Capital Management
Massachusetts
$328K -$56.3K -34,858 -15%
Morgan Stanley
15
Morgan Stanley
New York
$254K -$5.09K -3,149 -2%
Goldman Sachs
16
Goldman Sachs
New York
$229K +$86K +53,225 +61%
YIH
17
Y-Intercept (HK)
Hong Kong
$181K +$180K +111,425 New
Geode Capital Management
18
Geode Capital Management
Massachusetts
$179K -$654K -404,971 -79%
Susquehanna International Group
19
Susquehanna International Group
Pennsylvania
$147K +$55K +34,067 +60%
Qube Research & Technologies (QRT)
20
Qube Research & Technologies (QRT)
United Kingdom
$129K +$129K +79,541 New
Bank of America
21
Bank of America
North Carolina
$116K +$974 +603 +0.8%
AQR Capital Management
22
AQR Capital Management
Connecticut
$105K +$76.2K +47,142 +268%
CCA
23
Conservest Capital Advisors
Pennsylvania
$104K – – –
HF
24
HRT Financial
New York
$98K +$98.3K +60,829 New
Osaic Holdings
25
Osaic Holdings
Arizona
$96.6K +$79.2K +49,000 +460%
1
2 3 4

GUTS Hedge Fund Activity: Q2 2025 in Review

62 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Fractyl Health (GUTS) for Q2 2025, worth a combined $44.9M — up 51% from $29.7M a quarter earlier.

Sellers outnumbered buyers: 22 funds closed out of GUTS and 19 opened new positions — a net loss of 3 holders — while 20 trimmed existing stakes and 14 added.

The largest buyer was General Catalyst Group Management, opening a new position worth an estimated $7.89M. The largest seller was BlackRock, cutting an estimated $2.54M.

  • 62 institutional investors held Fractyl Health (GUTS) as of Q2 2025, down from 65 in Q1 2025.
  • Funds reported $44.9M of Fractyl Health stock for Q2 2025, up 51% quarter-over-quarter.
  • 19 funds opened new Fractyl Health positions in Q2 2025 and 22 closed out, a net change of -3 holders.
  • The largest Fractyl Health buyer in Q2 2025 was General Catalyst Group Management, an estimated $7.89M added.
  • The largest Fractyl Health seller in Q2 2025 was BlackRock, an estimated $2.54M sold.

Based on aggregated 13F filings for Q2 2025.