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Fractyl Health

83 hedge funds and large institutions have $33M invested in Fractyl Health in 2026 Q1 according to their latest regulatory filings, with 19 funds opening new positions, 14 increasing their positions, 27 reducing their positions, and 30 closing their positions.

New
Increased
Maintained
Reduced
Closed

14% less funds holding

Funds holding: 9783 (-14)

25% less funds holding in top 10

Funds holding in top 10: 43 (-1)

36.65% less ownership

Funds ownership: 82.04%45.39% (-37%)

37% less first-time investments, than exits

New positions opened: 19 | Existing positions closed: 30

48% less repeat investments, than reductions

Existing positions increased: 14 | Existing positions reduced: 27

87% less capital invested

Capital invested by funds: $247M → $33M (-$214M)

Holders
83
Holders Change
-14
Holders Change %
-14.43%
% of All Funds
1.02%
Holding in Top 10
3
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-25%
% of All Funds
0.04%
New
19
Increased
14
Reduced
27
Closed
30
Calls
$654K
Puts
Net Calls
+$654K
Net Calls Change
-$2.49M
Name Holding Trade Value Shares
Change
Change in
Stake
NCM
1
Nantahala Capital Management
Connecticut
$6.12M +$2.32M +2,518,079 +23%
6CM
2
683 Capital Management
New York
$3.08M +$627K +679,615 +11%
PFCS
3
Pale Fire Capital SE
Czech Republic
$2.71M +$2.5M +2,711,103 +84%
VCM
4
Vanguard Capital Management
Pennsylvania
$2.53M +$5.1M +5,533,006 New
CCM
5
Catalio Capital Management
New York
$2.51M
GCGM
6
General Catalyst Group Management
Massachusetts
$2.24M
DMC
7
Deer Management Company
New York
$2.19M
MC
8
Maverick Capital
Texas
$1.82M -$252K -273,686 -6%
WP
9
Woodline Partners
California
$1.03M -$3.01M -3,265,092 -59%
BlackRock
10
BlackRock
New York
$980K +$52.1K +56,519 +3%
MCM
11
M28 Capital Management
Connecticut
$850K
SCM
12
Silverarc Capital Management
Massachusetts
$779K -$7.5M -8,138,416 -83%
UBS Group
13
UBS Group
Switzerland
$743K +$468K +508,181 +46%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$657K +$158K +171,406 +14%
CM
15
CM Management
Florida
$641K +$553K +600,000 +75%
IC
16
Ikarian Capital
Texas
$504K
LGM
17
Logos Global Management
California
$458K -$92.2K -100,000 -9%
Marshall Wace
18
Marshall Wace
United Kingdom
$372K -$4.72M -5,118,949 -86%
VFT
19
Vanguard Fiduciary Trust
Pennsylvania
$278K +$559K +606,185 New
BGM
20
Burkehill Global Management
New York
$229K
Morgan Stanley
21
Morgan Stanley
New York
$227K -$148K -160,581 -24%
Two Sigma Investments
22
Two Sigma Investments
New York
$220K -$1.25M -1,360,399 -74%
State Street
23
State Street
Massachusetts
$213K -$44.3K -48,000 -9%
SC
24
Shay Capital
New York
$164K +$204K +221,297 +162%
BFM
25
Boothbay Fund Management
New York
$126K

GUTS Hedge Fund Activity: Q1 2026 in Review

83 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Fractyl Health (GUTS) for Q1 2026, worth a combined $33M — down 87% from $247M a quarter earlier.

Sellers outnumbered buyers: 30 funds closed out of GUTS and 19 opened new positions — a net loss of 11 holders — while 27 trimmed existing stakes and 14 added.

The largest buyer was Pale Fire Capital SE, adding an estimated $2.5M. The largest seller was Alyeska Investment Group, exiting entirely with an estimated $8.38M sold.

  • 83 institutional investors held Fractyl Health (GUTS) as of Q1 2026, down from 97 in Q4 2025.
  • Funds reported $33M of Fractyl Health stock for Q1 2026, down 87% quarter-over-quarter.
  • 19 funds opened new Fractyl Health positions in Q1 2026 and 30 closed out, a net change of -11 holders.
  • The largest Fractyl Health buyer in Q1 2026 was Pale Fire Capital SE, an estimated $2.5M added.
  • The largest Fractyl Health seller in Q1 2026 was Alyeska Investment Group, an estimated $8.38M sold.

Based on aggregated 13F filings for Q1 2026.