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Fractyl Health

74 hedge funds and large institutions have $145M invested in Fractyl Health in 2025 Q3 according to their latest regulatory filings, with 30 funds opening new positions, 18 increasing their positions, 14 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

224% more capital invested

Capital invested by funds: $44.9M → $145M (+$101M)

125.41% more ownership

Funds ownership: 56.54%181.94% (+125%)

67% more first-time investments, than exits

New positions opened: 30 | Existing positions closed: 18

29% more repeat investments, than reductions

Existing positions increased: 18 | Existing positions reduced: 14

19% more funds holding

Funds holding: 6274 (+12)

0% more funds holding in top 10

Funds holding in top 10: 44 (0)

Holders
74
Holders Change
+12
Holders Change %
+19.35%
% of All Funds
0.97%
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.05%
New
30
Increased
18
Reduced
14
Closed
18
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
NCM
1
Nantahala Capital Management
Connecticut
$19.3M +$15.7M +12,136,917 New
SCM
2
Silverarc Capital Management
Massachusetts
$16.9M +$13.5M +10,397,410 +5,132%
Alyeska Investment Group
3
Alyeska Investment Group
Illinois
$8.98M +$7.33M +5,648,371 New
WP
4
Woodline Partners
California
$8.76M +$6.37M +4,908,693 +821%
CCM
5
Catalio Capital Management
New York
$8.29M +$6.49M +5,000,000 +2,334%
RA
6
Rosalind Advisors
Ontario, Canada
$7.95M +$6.49M +5,000,000 New
GCGM
7
General Catalyst Group Management
Massachusetts
$7.77M
DMC
8
Deer Management Company
New York
$7.59M
HM
9
HCC Manager
Illinois
$7.43M
6CM
10
683 Capital Management
New York
$7.39M +$5.2M +4,005,000 +621%
MC
11
Maverick Capital
Texas
$6.76M
SCM
12
Soleus Capital Management
Connecticut
$3.98M +$3.24M +2,500,000 New
Point72 Asset Management
13
Point72 Asset Management
Connecticut
$3.48M +$2.84M +2,187,999 New
Vanguard Group
14
Vanguard Group
Pennsylvania
$3.05M +$1.05M +812,361 +73%
MCM
15
M28 Capital Management
Connecticut
$2.95M
IC
16
Ikarian Capital
Texas
$2.86M +$2.34M +1,800,000 New
Citadel Advisors
17
Citadel Advisors
Florida
$2.83M +$2.31M +1,782,356 New
Marshall Wace
18
Marshall Wace
United Kingdom
$2.81M +$2.3M +1,769,776 New
Massachusetts Financial Services
19
Massachusetts Financial Services
Massachusetts
$1.47M -$9.26K -7,138 -0.8%
Renaissance Technologies
20
Renaissance Technologies
New York
$1.23M +$1.01M +776,700 New
BlackRock
21
BlackRock
New York
$1.21M -$164K -126,714 -14%
UBS Group
22
UBS Group
Switzerland
$1.2M +$947K +729,754 +3,195%
AI
23
Alphabet Inc
California
$1.05M
BFM
24
Boothbay Fund Management
New York
$1.04M +$850K +655,200 New
HF
25
HRT Financial
New York
$977K +$719K +553,963 +911%

GUTS Hedge Fund Activity: Q3 2025 in Review

74 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Fractyl Health (GUTS) for Q3 2025, worth a combined $145M — up 224% from $44.9M a quarter earlier.

Buyers outnumbered sellers: 30 funds opened new GUTS positions and 18 closed out — a net gain of 12 holders — while 18 added to existing stakes and 14 trimmed.

The largest buyer was Nantahala Capital Management, opening a new position worth an estimated $15.7M. The largest seller was Y-Intercept (HK), exiting entirely with an estimated $181K sold.

  • 74 institutional investors held Fractyl Health (GUTS) as of Q3 2025, up from 62 in Q2 2025.
  • Funds reported $145M of Fractyl Health stock for Q3 2025, up 224% quarter-over-quarter.
  • 30 funds opened new Fractyl Health positions in Q3 2025 and 18 closed out, a net change of +12 holders.
  • The largest Fractyl Health buyer in Q3 2025 was Nantahala Capital Management, an estimated $15.7M added.
  • The largest Fractyl Health seller in Q3 2025 was Y-Intercept (HK), an estimated $181K sold.

Based on aggregated 13F filings for Q3 2025.