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Fractyl Health

74 hedge funds and large institutions have $145M invested in Fractyl Health in 2025 Q3 according to their latest regulatory filings, with 30 funds opening new positions, 18 increasing their positions, 14 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

224% more capital invested

Capital invested by funds: $44.9M → $145M (+$101M)

125.41% more ownership

Funds ownership: 56.54%181.94% (+125%)

67% more first-time investments, than exits

New positions opened: 30 | Existing positions closed: 18

29% more repeat investments, than reductions

Existing positions increased: 18 | Existing positions reduced: 14

19% more funds holding

Funds holding: 6274 (+12)

0% more funds holding in top 10

Funds holding in top 10: 44 (0)

Holders
74
Holders Change
+12
Holders Change %
+19.35%
% of All Funds
0.97%
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.05%
New
30
Increased
18
Reduced
14
Closed
18
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
CM
26
CM Management
Florida
$954K +$778K +600,000 New
BGM
27
Burkehill Global Management
New York
$795K +$649K +500,000 New
LGM
28
Logos Global Management
California
$795K +$649K +500,000 New
Goldman Sachs
29
Goldman Sachs
New York
$780K +$453K +349,390 +248%
Morgan Stanley
30
Morgan Stanley
New York
$684K +$355K +273,341 +174%
Millennium Management
31
Millennium Management
New York
$648K -$150K -115,306 -22%
Geode Capital Management
32
Geode Capital Management
Massachusetts
$469K +$239K +184,464 +167%
D.E. Shaw & Co
33
D.E. Shaw & Co
New York
$468K +$382K +294,290 New
SC
34
Shay Capital
New York
$453K +$370K +285,202 New
PEAK6
35
PEAK6
Illinois
$398K +$324K +250,000 New
GCP
36
GSA Capital Partners
United Kingdom
$285K +$232K +179,023 New
DC
37
Diametric Capital
Massachusetts
$200K +$141K +108,704 +642%
Bank of America
38
Bank of America
North Carolina
$141K +$21.9K +16,856 +23%
CCA
39
Conservest Capital Advisors
Pennsylvania
$102K
HighTower Advisors
40
HighTower Advisors
Illinois
$81.8K +$676 +521 +1%
JP Morgan Chase
41
JP Morgan Chase
New York
$80.7K +$65.8K +50,744 New
Osaic Holdings
42
Osaic Holdings
Arizona
$79K +$22.2K +17,100 +29%
CC
43
Centiva Capital
New York
$78.5K +$64K +49,340 New
XT
44
XTX Topco
Cayman Islands
$73.2K +$59.7K +46,047 New
BCM
45
Bridgeway Capital Management
Texas
$72.3K
State Street
46
State Street
Massachusetts
$64.9K
AIP
47
Arrowpoint Investment Partners
Singapore
$55.6K +$45.4K +35,000 New
PCM
48
Prelude Capital Management
New York
$55.3K +$45.1K +34,754 New
SRL
49
Scientech Research LLC
New Jersey
$48.6K +$39.7K +30,569 New
CPIG
50
Chicago Partners Investment Group
Illinois
$39.7K -$301 -232 -0.7%

GUTS Hedge Fund Activity: Q3 2025 in Review

74 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Fractyl Health (GUTS) for Q3 2025, worth a combined $145M — up 224% from $44.9M a quarter earlier.

Buyers outnumbered sellers: 30 funds opened new GUTS positions and 18 closed out — a net gain of 12 holders — while 18 added to existing stakes and 14 trimmed.

The largest buyer was Nantahala Capital Management, opening a new position worth an estimated $15.7M. The largest seller was Y-Intercept (HK), exiting entirely with an estimated $181K sold.

  • 74 institutional investors held Fractyl Health (GUTS) as of Q3 2025, up from 62 in Q2 2025.
  • Funds reported $145M of Fractyl Health stock for Q3 2025, up 224% quarter-over-quarter.
  • 30 funds opened new Fractyl Health positions in Q3 2025 and 18 closed out, a net change of +12 holders.
  • The largest Fractyl Health buyer in Q3 2025 was Nantahala Capital Management, an estimated $15.7M added.
  • The largest Fractyl Health seller in Q3 2025 was Y-Intercept (HK), an estimated $181K sold.

Based on aggregated 13F filings for Q3 2025.