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Structure Therapeutics
GPCR

Overview Fund Activity

163 hedge funds and large institutions have $1.65B invested in Structure Therapeutics in 2024 Q4 according to their latest regulatory filings, with 28 funds opening new positions, 65 increasing their positions, 49 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
163
Holders Change
+3
Holders Change %
+1.88%
% of All Funds
2.17%
Holding in Top 10
5
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-28.57%
% of All Funds
0.07%
New
28
Increased
65
Reduced
49
Closed
23
Calls
$28.1M
Puts
$17.3M
Net Calls
+$10.8M
Net Calls Change
+$8.67M

Top Buyers

1
DTC
Deep Track Capital
Connecticut
+$42.8M
2
VPC
Vestal Point Capital
New York
+$15.6M
3
Marshall Wace
Marshall Wace
United Kingdom
+$12.2M
4
Ameriprise
Ameriprise
Minnesota
+$8.75M
5
CCM
Camber Capital Management
Massachusetts
+$8.14M

Top Sellers

1
OCA
Octagon Capital Advisors
New York
-$52.6M
2
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
-$31.4M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
-$20.7M
4
APM
Avidity Partners Management
Texas
-$18.9M
5
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$18.7M
Name Holding Trade Value Shares
Change 		Shares
Change %
US Bancorp
151
US Bancorp
Minnesota
$2.74K +$2.39K +88 +677%
S
152
SignatureFD
Georgia
$2.71K – – –
VWM
153
Vermillion Wealth Management
Minnesota
$2.71K +$2.71K +100 New
CA
154
CoreCap Advisors
Michigan
$2.09K +$2.09K +77 New
CA
155
Clearstead Advisors
Ohio
$1.82K – – –
FFA
156
Fairfield Financial Advisors
Massachusetts
$1.6K – – –
WTA
157
Washington Trust Advisors
Massachusetts
$1.11K – – –
FDCDDQ
158
Federation des caisses Desjardins du Quebec
Quebec, Canada
$542 – – –
GRP
159
Global Retirement Partners
California
$271 +$271 +10 New
CFB
160
Cullen/Frost Bankers
Texas
$217 – – –
HNB
161
Huntington National Bank
Ohio
$54 – – –
PAS
162
Point72 Asia (Singapore)
Singapore
$23 +$23 +1 New
OCA
163
Octagon Capital Advisors
New York
– -$52.6M -1,198,000 Closed
T. Rowe Price Investment Management
164
T. Rowe Price Investment Management
Maryland
– -$31.4M -715,968 Closed
APM
165
Avidity Partners Management
Texas
– -$18.9M -430,900 Closed
BC
166
Boxer Capital
California
– -$17.6M -400,000 Closed
Adage Capital Partners
167
Adage Capital Partners
Massachusetts
– -$11M -250,000 Closed
TCM
168
Tang Capital Management
California
– -$6.34M -144,500 Closed
Hudson Bay Capital Management
169
Hudson Bay Capital Management
Connecticut
– -$3.14M -71,615 Closed
ACM
170
Altium Capital Management
New York
– -$3.07M -70,000 Closed
BOCH
171
Blue Owl Capital Holdings
New York
– -$2.85M -65,000 Closed
PM
172
Plustick Management
Virginia
– -$1.98M -45,000 Closed
YIH
173
Y-Intercept (HK)
Hong Kong
– -$1.79M -40,706 Closed
PA
174
Perceptive Advisors
New York
– -$1.53M -34,852 Closed
GCP
175
GSA Capital Partners
United Kingdom
– -$1.34M -30,464 Closed
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