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Structure Therapeutics

196 hedge funds and large institutions have $4.64B invested in Structure Therapeutics in 2025 Q4 according to their latest regulatory filings, with 70 funds opening new positions, 52 increasing their positions, 62 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

more funds holding in top 10

Funds holding in top 10:

more call options, than puts

Call options by funds: $ | Put options by funds: $

more capital invested

Capital invested by funds: $ → $

more first-time investments, than exits

New positions opened: | Existing positions closed:

26% more funds holding

Funds holding: 156196 (+40)

11.44% more ownership

Funds ownership: 98.33%109.77% (+11%)

16% less repeat investments, than reductions

Existing positions increased: 52 | Existing positions reduced: 62

Holders
196
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
16
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$62.6M
Puts
$18.2M
Net Calls
Net Calls Change

Top Sellers

1 -$45.8M
2 -$42.5M
3 -$38.3M
4
Invesco
Invesco
Georgia
-$18M
5
CCM
Catalio Capital Management
New York
-$16.3M
Name Holding Trade Value Shares
Change
Change in
Stake
PHS
76
PFM Health Sciences
California
$4.75M
SPS
77
Susquehanna Portfolio Strategies
Pennsylvania
$4.74M
BGM
78
Burkehill Global Management
New York
$4.17M
LP
79
Longaeva Partners
Illinois
$4.17M
BPC
80
Banque Pictet & Cie
Switzerland
$4.16M
Osaic Holdings
81
Osaic Holdings
Arizona
$4.12M
VOYA Investment Management
82
VOYA Investment Management
Georgia
$3.85M
Geode Capital Management
83
Geode Capital Management
Massachusetts
$3.84M
PHP
84
Parkman Healthcare Partners
Connecticut
$3.83M
Bank of Montreal
85
Bank of Montreal
Ontario, Canada
$3.68M
BPMC
86
Buckland Partners Management Co
New York
$3.48M
IHAM
87
Integral Health Asset Management
New York
$3.48M
SGM
88
Seven Grand Managers
New York
$3.48M
AA
89
ALPS Advisors
Colorado
$3.46M
PC
90
Pier Capital
Connecticut
$3.39M
State Street
91
State Street
Massachusetts
$3.35M
AP
92
Antipodes Partners
Australia
$3.22M
Raymond James Financial
93
Raymond James Financial
Florida
$3.09M
Mariner
94
Mariner
Kansas
$3.07M
HT
95
Headlands Technologies
Illinois
$3.04M
SFM
96
Sphera Funds Management
Israel
$2.85M
ACM
97
ACT Capital Management
Pennsylvania
$2.68M
EI
98
EAM Investors
California
$2.65M
DCM
99
DAFNA Capital Management
California
$2.57M
Tudor Investment Corp
100
Tudor Investment Corp
Connecticut
$2.44M