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Structure Therapeutics
GPCR

Overview Fund Activity

151 hedge funds and large institutions have $981M invested in Structure Therapeutics in 2025 Q1 according to their latest regulatory filings, with 24 funds opening new positions, 46 increasing their positions, 50 reducing their positions, and 35 closing their positions.

Holders
151
Holders Change
-12
Holders Change %
-7.36%
% of All Funds
2.05%
Holding in Top 10
1
Holding in Top 10 Change
-4
Holding in Top 10 Change %
-80%
% of All Funds
0.01%
New
24
Increased
46
Reduced
50
Closed
35
Calls
$12.4M
Puts
$11.7M
Net Calls
+$750K
Net Calls Change
-$10.1M

Top Buyers

1
DTC
1
Deep Track Capital
Connecticut
$71M
2
Morgan Stanley
2
Morgan Stanley
New York
$12M
3
RAM
3
Readystate Asset Management
Illinois
$8.33M
4
Janus Henderson Group
4
Janus Henderson Group
United Kingdom
$86.1M
5
Handelsbanken Fonder
5
Handelsbanken Fonder
Sweden
$6.58M

Top Sellers

1
Capital Research Global Investors
1
Capital Research Global Investors
California
$37.5M
2
Federated Hermes
2
Federated Hermes
Pennsylvania
$20.3M
3
DCM
3
Driehaus Capital Management
Illinois
$22M
4
BCM
4
Boxer Capital Management
California
$0
5
T. Rowe Price Associates
5
T. Rowe Price Associates
Maryland
$13.5M
Name Holding Trade Value Shares
Change 		Shares
Change %
American Century Companies
26
American Century Companies
Missouri
$8.83M -$1.77M -102,415 -17%
RAM
27
Readystate Asset Management
Illinois
$8.33M +$4.71M +271,899 +130%
LGM
28
Logos Global Management
California
$7.36M -$4.76M -275,000 -39%
FCMV
29
Foresite Capital Management VI
California
$7.27M – – –
Invesco
30
Invesco
Georgia
$6.83M +$392K +22,619 +6%
Handelsbanken Fonder
31
Handelsbanken Fonder
Sweden
$6.58M +$3.72M +215,000 +130%
DM
32
Deerfield Management
New York
$6.46M – – –
BBA
33
Baker Bros. Advisors
New York
$6.26M – – –
HH
34
HSG Holding
Hong Kong
$6.2M – – –
Goldman Sachs
35
Goldman Sachs
New York
$5.62M -$4.47M -258,430 -44%
CCM
36
Camber Capital Management
Massachusetts
$5.19M – – –
MIM
37
Monashee Investment Management
Massachusetts
$5.07M +$2.78M +160,862 +122%
IC
38
Ikarian Capital
Texas
$4.57M -$346K -20,000 -7%
Aberdeen Group
39
Aberdeen Group
United Kingdom
$4.31M +$1.34M +77,511 +45%
ACH
40
ArrowMark Colorado Holdings
Colorado
$4.24M +$213K +12,277 +5%
UBS Group
41
UBS Group
Switzerland
$4.12M -$102K -5,866 -2%
Point72 Asset Management
42
Point72 Asset Management
Connecticut
$3.97M -$4.28M -247,267 -52%
BG
43
Bellevue Group
Switzerland
$3.84M -$4.56M -263,335 -54%
CS
44
Candriam SCA
Luxembourg
$3.71M -$23.5K -1,358 -0.6%
PC
45
Pier Capital
Connecticut
$3.68M +$1.38M +79,916 +60%
Balyasny Asset Management
46
Balyasny Asset Management
Illinois
$3.5M +$3.5M +202,483 New
SCM
47
Silverarc Capital Management
Massachusetts
$3.26M +$618K +35,674 +23%
WP
48
Woodline Partners
California
$3.04M -$2.74M -158,477 -47%
NCM
49
Nantahala Capital Management
Connecticut
$2.92M -$908K -52,447 -24%
SFI
50
Susquehanna Fundamental Investments
Pennsylvania
$2.73M +$2.73M +157,961 New
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