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Structure Therapeutics
GPCR

84 hedge funds and large institutions have $1.64B invested in Structure Therapeutics in 2023 Q3 according to their latest regulatory filings, with 42 funds opening new positions, 29 increasing their positions, 6 reducing their positions, and 6 closing their positions.

New
Increased
Maintained
Reduced
Closed

600% more first-time investments, than exits

New positions opened: 42 | Existing positions closed: 6

383% more repeat investments, than reductions

Existing positions increased: 29 | Existing positions reduced: 6

175% more funds holding in top 10

Funds holding in top 10: 4 → 11 (+7)

135% more capital invested

Capital invested by funds: $699M → $1.64B (+$944M)

75% more funds holding

Funds holding: 48 → 84 (+36)

14.1% more ownership

Funds ownership: 16.43% → 30.53% (+14%)

Holders
84
Holders Change
+36
Holders Change %
+75%
% of All Funds
1.33%
Holding in Top 10
11
Holding in Top 10 Change
+7
Holding in Top 10 Change %
+175%
% of All Funds
0.17%
New
42
Increased
29
Reduced
6
Closed
6
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$64.9M
2
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$51.8M
3
DCM
Driehaus Capital Management
Illinois
+$40.4M
4
TCM
TCG Crossover Management
California
+$37.1M
5
HH
HSG Holding
Hong Kong
+$34.3M

Top Sellers

Rank Fund Capital Flow
1
MIM
Monashee Investment Management
Massachusetts
-$23.8M
2
DTC
Deep Track Capital
Connecticut
-$23.6M
3
OCA
Octagon Capital Advisors
New York
-$3.12M
4
NCM
Nantahala Capital Management
Connecticut
-$2.08M
5
Renaissance Technologies
Renaissance Technologies
New York
-$1.37M
Name Holding Trade Value Shares
Change 		Change in
Stake
Millennium Management
26
Millennium Management
New York
$15.1M +$8.24M +255,648 +578%
Holocene Advisors
27
Holocene Advisors
New York
$14.2M +$9.07M +281,291 New
Franklin Resources
28
Franklin Resources
California
$12.6M +$354 +11 +0%
MB
29
MPM BioImpact
Massachusetts
$11.6M +$7.44M +230,761 New
SI
30
Sofinnova Investments
California
$10.2M +$6.51M +202,119 New
WP
31
Woodline Partners
California
$8.57M – – –
ACM
32
Altium Capital Management
New York
$7.82M +$5M +155,000 New
TD Asset Management
33
TD Asset Management
Ontario, Canada
$7.67M +$2.56M +79,467 +109%
Victory Capital Management
34
Victory Capital Management
Texas
$7.61M +$4.86M +150,958 New
IC
35
Ikarian Capital
Texas
$6.95M +$4.44M +137,824 New
GC
36
GMT Capital
Georgia
$5.71M +$3.65M +113,200 New
Invesco
37
Invesco
Georgia
$5.7M +$3.64M +113,093 New
Marshall Wace
38
Marshall Wace
United Kingdom
$5.42M +$3.46M +107,518 New
Capital World Investors
39
Capital World Investors
California
$5.03M +$3.24M +100,400 New
FAM
40
Fred Alger Management
New York
$5.01M +$2.86M +88,828 +845%
VOYA Investment Management
41
VOYA Investment Management
Georgia
$4.36M +$2.79M +86,474 New
HS
42
HighVista Strategies
Massachusetts
$3.77M +$2.41M +74,832 New
Goldman Sachs
43
Goldman Sachs
New York
$3.6M +$2.3M +71,433 New
WC
44
Wexford Capital
Florida
$3.43M +$2.19M +67,978 New
Manulife (Manufacturers Life Insurance)
45
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$2.78M +$466K +14,455 +36%
GTC
46
Ghost Tree Capital
New York
$2.77M +$1.77M +55,000 New
PIM
47
Platinum Investment Management
Australia
$2.65M +$1.21M +37,461 +250%
ACH
48
ArrowMark Colorado Holdings
Colorado
$2.52M – – –
EI
49
EAM Investors
California
$2.22M +$1.42M +43,978 New
JP Morgan Chase
50
JP Morgan Chase
New York
$1.99M +$1.27M +39,559 New
1
2
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GPCR Hedge Fund Activity: Q3 2023 in Review

84 of the 6,301 institutional investors tracked by Wall St. Rank reported a position in Structure Therapeutics (GPCR) for Q3 2023, worth a combined $1.64B — up 135% from $699M a quarter earlier.

Buyers outnumbered sellers: 42 funds opened new GPCR positions and 6 closed out — a net gain of 36 holders — while 29 added to existing stakes and 6 trimmed.

The largest buyer was Janus Henderson Group, adding an estimated $64.9M. The largest seller was Monashee Investment Management, cutting an estimated $23.8M.

  • 84 institutional investors held Structure Therapeutics (GPCR) as of Q3 2023, up from 48 in Q2 2023.
  • Funds reported $1.64B of Structure Therapeutics stock for Q3 2023, up 135% quarter-over-quarter.
  • 42 funds opened new Structure Therapeutics positions in Q3 2023 and 6 closed out, a net change of +36 holders.
  • The largest Structure Therapeutics buyer in Q3 2023 was Janus Henderson Group, an estimated $64.9M added.
  • The largest Structure Therapeutics seller in Q3 2023 was Monashee Investment Management, an estimated $23.8M sold.

Based on aggregated 13F filings for Q3 2023.