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Structure Therapeutics
GPCR

48 hedge funds and large institutions have $699M invested in Structure Therapeutics in 2023 Q2 according to their latest regulatory filings, with 14 funds opening new positions, 11 increasing their positions, 10 reducing their positions, and 4 closing their positions.

New
Increased
Maintained
Reduced
Closed

300% more funds holding in top 10

Funds holding in top 10: 1 → 4 (+3)

250% more first-time investments, than exits

New positions opened: 14 | Existing positions closed: 4

102% more capital invested

Capital invested by funds: $346M → $699M (+$353M)

26% more funds holding

Funds holding: 38 → 48 (+10)

10% more repeat investments, than reductions

Existing positions increased: 11 | Existing positions reduced: 10

2.99% more ownership

Funds ownership: 13.45% → 16.43% (+3%)

Holders
48
Holders Change
+10
Holders Change %
+26.32%
% of All Funds
0.75%
Holding in Top 10
4
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+300%
% of All Funds
0.06%
New
14
Increased
11
Reduced
10
Closed
4
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
MIM
Monashee Investment Management
Massachusetts
+$33.7M
2
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$27.7M
3
CC
Casdin Capital
New York
+$8.97M
4
DM
Deerfield Management
New York
+$7.08M
5
DCM
Driehaus Capital Management
Illinois
+$5.48M

Top Sellers

Rank Fund Capital Flow
1
Janus Henderson Group
Janus Henderson Group
United Kingdom
-$7.54M
2
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$2.8M
3
Franklin Resources
Franklin Resources
California
-$2.08M
4
AG
Artal Group
Luxembourg
-$1.78M
5
Federated Hermes
Federated Hermes
Pennsylvania
-$1.07M
Name Holding Trade Value Shares
Change 		Change in
Stake
NCM
26
Nantahala Capital Management
Connecticut
$2.08M – – –
Millennium Management
27
Millennium Management
New York
$1.84M +$246K +8,767 +25%
Prudential Financial
28
Prudential Financial
New Jersey
$1.75M – – –
Manulife (Manufacturers Life Insurance)
29
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$1.69M +$1.14M +40,631 New
APM
30
Avidity Partners Management
Texas
$1.57M +$1.06M +37,800 New
SFG
31
SVB Financial Group
Texas
$1.47M – – –
Renaissance Technologies
32
Renaissance Technologies
New York
$1.37M +$922K +32,900 New
CUAMC
33
China Universal Asset Management Company
China
$1.13M +$764K +27,267 New
MS
34
Maven Securities
Jersey
$1.04M +$701K +25,000 New
LCM
35
Lynx1 Capital Management
Puerto Rico
$956K – – –
WMSA
36
Weiss Multi-Strategy Advisers
New York
$631K +$425K +15,173 New
PIM
37
Platinum Investment Management
Australia
$624K – – –
State Street
38
State Street
Massachusetts
$476K +$321K +11,460 New
FAM
39
Fred Alger Management
New York
$437K +$295K +10,512 New
Geode Capital Management
40
Geode Capital Management
Massachusetts
$426K +$287K +10,257 New
UOC
41
UBS O'Connor
Illinois
$424K -$332K -11,857 -54%
VEA
42
Virtus ETF Advisers
New York
$146K +$98.4K +3,513 New
Bank of America
43
Bank of America
North Carolina
$70K +$47.2K +1,684 New
Barclays
44
Barclays
United Kingdom
$47.1K +$31.7K +1,132 New
S
45
SignatureFD
Georgia
$4.16K – – –
TRCT
46
Tower Research Capital (TRC)
New York
$2.79K -$925 -33 -33%
UBS Group
47
UBS Group
Switzerland
$83 +$56 +2 New
PAM
48
Pinpoint Asset Management
Hong Kong
$37 +$25.2K +900 New
AG
49
Artal Group
Luxembourg
– -$1.78M -75,000 Closed
PMEF
50
Point72 Middle East FZE
United Arab Emirates
– -$202K -8,474 Closed
1
2
3

GPCR Hedge Fund Activity: Q2 2023 in Review

48 of the 6,369 institutional investors tracked by Wall St. Rank reported a position in Structure Therapeutics (GPCR) for Q2 2023, worth a combined $699M — up 102% from $346M a quarter earlier.

Buyers outnumbered sellers: 14 funds opened new GPCR positions and 4 closed out — a net gain of 10 holders — while 11 added to existing stakes and 10 trimmed.

The largest buyer was Monashee Investment Management, adding an estimated $33.7M. The largest seller was Janus Henderson Group, cutting an estimated $7.54M.

  • 48 institutional investors held Structure Therapeutics (GPCR) as of Q2 2023, up from 38 in Q1 2023.
  • Funds reported $699M of Structure Therapeutics stock for Q2 2023, up 102% quarter-over-quarter.
  • 14 funds opened new Structure Therapeutics positions in Q2 2023 and 4 closed out, a net change of +10 holders.
  • The largest Structure Therapeutics buyer in Q2 2023 was Monashee Investment Management, an estimated $33.7M added.
  • The largest Structure Therapeutics seller in Q2 2023 was Janus Henderson Group, an estimated $7.54M sold.

Based on aggregated 13F filings for Q2 2023.