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Guardant Health

394 hedge funds and large institutions have $7.65B invested in Guardant Health in 2025 Q3 according to their latest regulatory filings, with 71 funds opening new positions, 134 increasing their positions, 132 reducing their positions, and 39 closing their positions.

New
Increased
Maintained
Reduced
Closed

82% more first-time investments, than exits

New positions opened: 71 | Existing positions closed: 39

50% more funds holding in top 10

Funds holding in top 10: 69 (+3)

18% more capital invested

Capital invested by funds: $6.47B → $7.65B (+$1.19B)

8% more funds holding

Funds holding: 364394 (+30)

2% more repeat investments, than reductions

Existing positions increased: 134 | Existing positions reduced: 132

10% less call options, than puts

Call options by funds: $156M | Put options by funds: $173M

2.09% less ownership

Funds ownership: 100.34%98.24% (-2.1%)

Holders
394
Holders Change
+30
Holders Change %
+8.24%
% of All Funds
5.17%
Holding in Top 10
9
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+50%
% of All Funds
0.12%
New
71
Increased
134
Reduced
132
Closed
39
Calls
$156M
Puts
$173M
Net Calls
-$16.8M
Net Calls Change
+$20.6M
Name Holding Trade Value Shares
Change
Change in
Stake
EP
151
Edgestream Partners
New Jersey
$2.41M -$648K -11,919 -24%
HighTower Advisors
152
HighTower Advisors
Illinois
$2.37M -$11.8K -217 -0.6%
Capstone Investment Advisors
153
Capstone Investment Advisors
New York
$2.36M +$1.23M +22,657 +150%
ERSOT
154
Employees Retirement System of Texas
Texas
$2.33M
MCP
155
Meridiem Capital Partners
Texas
$2.29M -$767K -14,101 -28%
Comerica Bank
156
Comerica Bank
Texas
$2.29M -$54.8K -1,007 -3%
CFM
157
Capricorn Fund Managers
United Kingdom
$2.26M +$1.97M +36,200 New
Zurich Cantonal Bank
158
Zurich Cantonal Bank
Switzerland
$2.17M +$51.6K +948 +3%
D.E. Shaw & Co
159
D.E. Shaw & Co
New York
$2.08M +$1.81M +33,347 New
PFSRSONJ
160
Police & Firemen's Retirement System of New Jersey
New Jersey
$2.08M +$343K +6,299 +23%
ASRS
161
Arizona State Retirement System
Arizona
$2.06M +$33K +606 +2%
State Board of Administration of Florida Retirement System
162
State Board of Administration of Florida Retirement System
Florida
$2.01M
US Bancorp
163
US Bancorp
Minnesota
$2M -$107K -1,960 -6%
Susquehanna International Group
164
Susquehanna International Group
Pennsylvania
$1.98M -$8.25M -151,718 -83%
OCM
165
One Capital Management
California
$1.98M +$520K +9,556 +43%
SAM
166
Simplify Asset Management
Nevada
$1.94M +$243K +4,469 +17%
VFA
167
Values First Advisors
Tennessee
$1.94M -$81.4K -1,497 -5%
Canada Life
168
Canada Life
Manitoba, Canada
$1.93M -$76.3K -1,403 -4%
SO
169
STRS Ohio
Ohio
$1.91M +$549K +10,100 +50%
Handelsbanken Fonder
170
Handelsbanken Fonder
Sweden
$1.85M
DFCM
171
Dark Forest Capital Management
Puerto Rico
$1.78M -$2.48M -45,549 -62%
PCM
172
Prelude Capital Management
New York
$1.72M +$135K +2,476 +10%
Natixis Advisors
173
Natixis Advisors
Massachusetts
$1.68M -$20.9K -384 -1%
MMEA
174
Main Management ETF Advisors
California
$1.65M +$277K +5,093 +24%
Osaic Holdings
175
Osaic Holdings
Arizona
$1.64M -$268K -4,935 -17%

GH Hedge Fund Activity: Q3 2025 in Review

394 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Guardant Health (GH) for Q3 2025, worth a combined $7.65B — up 18% from $6.47B a quarter earlier.

Buyers outnumbered sellers: 71 funds opened new GH positions and 39 closed out — a net gain of 32 holders — while 134 added to existing stakes and 132 trimmed.

The largest buyer was T. Rowe Price Associates, adding an estimated $134M. The largest seller was Citadel Advisors, cutting an estimated $143M.

  • 394 institutional investors held Guardant Health (GH) as of Q3 2025, up from 364 in Q2 2025.
  • Funds reported $7.65B of Guardant Health stock for Q3 2025, up 18% quarter-over-quarter.
  • 71 funds opened new Guardant Health positions in Q3 2025 and 39 closed out, a net change of +32 holders.
  • The largest Guardant Health buyer in Q3 2025 was T. Rowe Price Associates, an estimated $134M added.
  • The largest Guardant Health seller in Q3 2025 was Citadel Advisors, an estimated $143M sold.

Based on aggregated 13F filings for Q3 2025.