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Fulcrum Therapeutics

122 hedge funds and large institutions have $374M invested in Fulcrum Therapeutics in 2025 Q2 according to their latest regulatory filings, with 24 funds opening new positions, 34 increasing their positions, 46 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed

874% more call options, than puts

Call options by funds: $6.27M | Put options by funds: $643K

152% more capital invested

Capital invested by funds: $148M → $374M (+$226M)

26% more first-time investments, than exits

New positions opened: 24 | Existing positions closed: 19

5.62% more ownership

Funds ownership: 95.16%100.78% (+5.6%)

4% more funds holding

Funds holding: 117122 (+5)

26% less repeat investments, than reductions

Existing positions increased: 34 | Existing positions reduced: 46

Holders
122
Holders Change
+5
Holders Change %
+4.27%
% of All Funds
1.61%
Holding in Top 10
2
Holding in Top 10 Change
+2
Holding in Top 10 Change %
% of All Funds
0.03%
New
24
Increased
34
Reduced
46
Closed
19
Calls
$6.27M
Puts
$643K
Net Calls
+$5.62M
Net Calls Change
+$5.51M
Name Holding Trade Value Shares
Change
Change in
Stake
PP
101
PrairieView Partners
Minnesota
$34K
BC
102
BIT Capital
Germany
$33.2K +$25.8K +4,832 New
Nisa Investment Advisors
103
Nisa Investment Advisors
Missouri
$29.5K +$1.42K +266 +7%
Royal Bank of Canada
104
Royal Bank of Canada
Ontario, Canada
$29K +$8.86K +1,656 +65%
FFA
105
Farther Finance Advisors
California
$23.5K +$7.46K +1,394 +69%
California State Teachers Retirement System (CalSTRS)
106
California State Teachers Retirement System (CalSTRS)
California
$22.9K -$6.23K -1,164 -26%
PAS
107
Point72 Asia (Singapore)
Singapore
$20.9K +$16.2K +3,031 New
PD
108
Point72 (DIFC)
United Arab Emirates
$18.3K +$14.3K +2,665 New
IA
109
IFP Advisors
Florida
$16.1K -$6.44K -1,204 -43%
AB
110
Amalgamated Bank
New York
$15K
US Bancorp
111
US Bancorp
Minnesota
$13.1K -$1.01K -189 -9%
PNC Financial Services Group
112
PNC Financial Services Group
Pennsylvania
$9.97K +$4.94K +923 +175%
SCM
113
Sterling Capital Management
North Carolina
$9.21K +$4.16K +778 +139%
National Bank of Canada
114
National Bank of Canada
Quebec, Canada
$3.25K -$7.95K -1,487 -76%
RA
115
Rise Advisors
New York
$2.39K +$1.86K +348 New
PWA
116
Physician Wealth Advisors
Utah
$1.95K +$1.51K +283 New
EWA
117
EverSource Wealth Advisors
Alabama
$1.5K +$1.17K +218 New
RWM
118
Rialto Wealth Management
New York
$1.09K
Carson Wealth (CWM LLC)
119
Carson Wealth (CWM LLC)
Nebraska
$1K +$760 +142 +330%
Osaic Holdings
120
Osaic Holdings
Arizona
$619 +$481 +90 New
SS
121
SBI Securities
Japan
$179
TWD
122
True Wealth Design
Ohio
$111 +$32 +6 +60%
SC
123
Shay Capital
New York
-$646K -224,305 Closed
Verition Fund Management
124
Verition Fund Management
Connecticut
-$188K -65,388 Closed
CSS
125
Cubist Systematic Strategies
Connecticut
-$164K -57,070 Closed

FULC Hedge Fund Activity: Q2 2025 in Review

122 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Fulcrum Therapeutics (FULC) for Q2 2025, worth a combined $374M — up 152% from $148M a quarter earlier.

Buyers outnumbered sellers: 24 funds opened new FULC positions and 19 closed out — a net gain of 5 holders — while 34 added to existing stakes and 46 trimmed.

The largest buyer was Adage Capital Partners, adding an estimated $8.5M. The largest seller was Nantahala Capital Management, cutting an estimated $2.86M.

  • 122 institutional investors held Fulcrum Therapeutics (FULC) as of Q2 2025, up from 117 in Q1 2025.
  • Funds reported $374M of Fulcrum Therapeutics stock for Q2 2025, up 152% quarter-over-quarter.
  • 24 funds opened new Fulcrum Therapeutics positions in Q2 2025 and 19 closed out, a net change of +5 holders.
  • The largest Fulcrum Therapeutics buyer in Q2 2025 was Adage Capital Partners, an estimated $8.5M added.
  • The largest Fulcrum Therapeutics seller in Q2 2025 was Nantahala Capital Management, an estimated $2.86M sold.

Based on aggregated 13F filings for Q2 2025.