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Fulcrum Therapeutics

117 hedge funds and large institutions have $148M invested in Fulcrum Therapeutics in 2025 Q1 according to their latest regulatory filings, with 17 funds opening new positions, 31 increasing their positions, 44 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed

270% more call options, than puts

Call options by funds: $148K | Put options by funds: $40K

0.74% less ownership

Funds ownership: 95.9%95.16% (-0.74%)

2% less funds holding

Funds holding: 119117 (-2)

11% less first-time investments, than exits

New positions opened: 17 | Existing positions closed: 19

30% less repeat investments, than reductions

Existing positions increased: 31 | Existing positions reduced: 44

39% less capital invested

Capital invested by funds: $243M → $148M (-$95M)

Holders
117
Holders Change
-2
Holders Change %
-1.68%
% of All Funds
1.57%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
17
Increased
31
Reduced
44
Closed
19
Calls
$148K
Puts
$40K
Net Calls
+$108K
Net Calls Change
-$5.12M
Name Holding Trade Value Shares
Change
Change in
Stake
Simplex Trading
101
Simplex Trading
Illinois
$8K -$27.3K -7,429 -71%
Royal Bank of Canada
102
Royal Bank of Canada
Ontario, Canada
$7K -$12K -3,266 -56%
US Bancorp
103
US Bancorp
Minnesota
$6.05K +$7.71K +2,100 New
AB
104
Amalgamated Bank
New York
$6K
National Bank of Canada
105
National Bank of Canada
Quebec, Canada
$5.64K +$5.51K +1,500 +326%
FFA
106
Farther Finance Advisors
California
$5.58K +$7.42K +2,021 New
CIAM
107
Caitong International Asset Management
Hong Kong
$4.34K +$5K +1,362 +939%
SPIA
108
Steward Partners Investment Advisory
New York
$2.27K
UBS AM
109
UBS AM
Illinois
$2.02K +$2.58K +703 New
SCM
110
Sterling Capital Management
North Carolina
$1.62K -$2.49K -678 -55%
PNC Financial Services Group
111
PNC Financial Services Group
Pennsylvania
$1.51K +$1.91K +521 +10,420%
Russell Investments Group
112
Russell Investments Group
United Kingdom
$622 -$360 -98 -31%
RWM
113
Rialto Wealth Management
New York
$458 +$584 +159 New
CCM
114
Coldstream Capital Management
Washington
$302 +$386 +105 New
SS
115
SBI Securities
Japan
$75
TWD
116
True Wealth Design
Ohio
$29 +$37 +10 New
PA
117
Perceptive Advisors
New York
-$1.12M -238,000 Closed
Wellington Management Group
118
Wellington Management Group
Massachusetts
-$809K -172,158 Closed
State Board of Administration of Florida Retirement System
119
State Board of Administration of Florida Retirement System
Florida
-$614K -130,693 Closed
Mackenzie Financial
120
Mackenzie Financial
Ontario, Canada
-$555K -118,025 Closed
LP
121
LMR Partners
United Kingdom
-$529K -112,500 Closed
ACM
122
Altium Capital Management
New York
-$526K -111,812 Closed
NRD
123
Nebula Research & Development
New York
-$353K -75,140 Closed
MA
124
MYDA Advisors
New York
-$301K -63,970 Closed
B
125
Bailard
California
-$169K -35,900 Closed

FULC Hedge Fund Activity: Q1 2025 in Review

117 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Fulcrum Therapeutics (FULC) for Q1 2025, worth a combined $148M — down 39% from $243M a quarter earlier.

Sellers outnumbered buyers: 19 funds closed out of FULC and 17 opened new positions — a net loss of 2 holders — while 44 trimmed existing stakes and 31 added.

The largest buyer was Suvretta Capital Management, adding an estimated $6.35M. The largest seller was Morgan Stanley, cutting an estimated $4.58M.

  • 117 institutional investors held Fulcrum Therapeutics (FULC) as of Q1 2025, down from 119 in Q4 2024.
  • Funds reported $148M of Fulcrum Therapeutics stock for Q1 2025, down 39% quarter-over-quarter.
  • 17 funds opened new Fulcrum Therapeutics positions in Q1 2025 and 19 closed out, a net change of -2 holders.
  • The largest Fulcrum Therapeutics buyer in Q1 2025 was Suvretta Capital Management, an estimated $6.35M added.
  • The largest Fulcrum Therapeutics seller in Q1 2025 was Morgan Stanley, an estimated $4.58M sold.

Based on aggregated 13F filings for Q1 2025.