Fulcrum Therapeutics
FULC
129 hedge funds and large institutions have $496M invested in Fulcrum Therapeutics in 2025 Q3 according to their latest regulatory filings, with 26 funds opening new positions, 40 increasing their positions, 43 reducing their positions, and 18 closing their positions.
1,213% more call options, than puts
Call options by funds: $1.64M | Put options by funds: $125K
44% more first-time investments, than exits
New positions opened: 26 | Existing positions closed: 18
32% more capital invested
Capital invested by funds: $374M → $496M (+$121M)
6% more funds holding
Funds holding: 122 → 129 (+7)
0% more funds holding in top 10
Funds holding in top 10: 2 → 2 (0)
7% less repeat investments, than reductions
Existing positions increased: 40 | Existing positions reduced: 43
1.34% less ownership
Funds ownership: 100.78% → 99.44% (-1.3%)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Royal Bank of Canada
Toronto,
Ontario, Canada
|
+$7.21M |
| 2 |
IC
Ikarian Capital
Dallas,
Texas
|
+$6.23M |
| 3 |
Citadel Advisors
Miami,
Florida
|
+$4.98M |
| 4 |
BFM
Boothbay Fund Management
New York
|
+$3.89M |
| 5 |
NCM
Nantahala Capital Management
New Canaan,
Connecticut
|
+$2.77M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Adage Capital Partners
Boston,
Massachusetts
|
-$15.6M |
| 2 |
WP
Woodline Partners
San Francisco,
California
|
-$6.18M |
| 3 |
BlackRock
New York
|
-$4.86M |
| 4 |
Goldman Sachs
New York
|
-$4.03M |
| 5 |
Point72 Asset Management
Stamford,
Connecticut
|
-$3.43M |
FULC Hedge Fund Activity: Q3 2025 in Review
129 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Fulcrum Therapeutics (FULC) for Q3 2025, worth a combined $496M — up 32% from $374M a quarter earlier.
Buyers outnumbered sellers: 26 funds opened new FULC positions and 18 closed out — a net gain of 8 holders — while 40 added to existing stakes and 43 trimmed.
The largest buyer was Royal Bank of Canada, adding an estimated $7.21M. The largest seller was Adage Capital Partners, cutting an estimated $15.6M.
- 129 institutional investors held Fulcrum Therapeutics (FULC) as of Q3 2025, up from 122 in Q2 2025.
- Funds reported $496M of Fulcrum Therapeutics stock for Q3 2025, up 32% quarter-over-quarter.
- 26 funds opened new Fulcrum Therapeutics positions in Q3 2025 and 18 closed out, a net change of +8 holders.
- The largest Fulcrum Therapeutics buyer in Q3 2025 was Royal Bank of Canada, an estimated $7.21M added.
- The largest Fulcrum Therapeutics seller in Q3 2025 was Adage Capital Partners, an estimated $15.6M sold.
Based on aggregated 13F filings for Q3 2025.