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Fulcrum Therapeutics

122 hedge funds and large institutions have $374M invested in Fulcrum Therapeutics in 2025 Q2 according to their latest regulatory filings, with 24 funds opening new positions, 34 increasing their positions, 46 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed

874% more call options, than puts

Call options by funds: $6.27M | Put options by funds: $643K

152% more capital invested

Capital invested by funds: $148M → $374M (+$226M)

26% more first-time investments, than exits

New positions opened: 24 | Existing positions closed: 19

5.62% more ownership

Funds ownership: 95.16%100.78% (+5.6%)

4% more funds holding

Funds holding: 117122 (+5)

26% less repeat investments, than reductions

Existing positions increased: 34 | Existing positions reduced: 46

Holders
122
Holders Change
+5
Holders Change %
+4.27%
% of All Funds
1.61%
Holding in Top 10
2
Holding in Top 10 Change
+2
Holding in Top 10 Change %
% of All Funds
0.03%
New
24
Increased
34
Reduced
46
Closed
19
Calls
$6.27M
Puts
$643K
Net Calls
+$5.62M
Net Calls Change
+$5.51M
Name Holding Trade Value Shares
Change
Change in
Stake
SO
51
STRS Ohio
Ohio
$517K -$86.1K -16,100 -18%
AllianceBernstein
52
AllianceBernstein
Tennessee
$513K +$48.1K +9,000 +14%
SAM
53
Simplify Asset Management
Nevada
$503K -$42.7K -7,980 -10%
T. Rowe Price Associates
54
T. Rowe Price Associates
Maryland
$475K -$6.1K -1,140 -2%
JGC
55
J. Goldman & Co
New York
$464K +$253K +47,250 +233%
Franklin Resources
56
Franklin Resources
California
$413K +$188K +35,201 +142%
ACP
57
Acuta Capital Partners
California
$410K +$319K +59,650 New
Two Sigma Investments
58
Two Sigma Investments
New York
$406K -$488K -91,309 -61%
Aberdeen Group
59
Aberdeen Group
United Kingdom
$404K +$314K +58,696 New
ACM
60
ADAR1 Capital Management
Texas
$367K -$2.34M -437,183 -89%
HSBC Holdings
61
HSBC Holdings
United Kingdom
$357K -$136K -25,425 -34%
LP
62
LMR Partners
United Kingdom
$344K +$267K +50,000 New
Bank of America
63
Bank of America
North Carolina
$316K -$54.3K -10,146 -18%
IQI
64
Integrated Quantitative Investments
Washington
$283K +$220K +41,106 New
AI
65
Allostery Investments
Connecticut
$278K +$216K +40,353 New
Wells Fargo
66
Wells Fargo
California
$232K +$17.3K +3,228 +11%
GCP
67
GSA Capital Partners
United Kingdom
$224K +$174K +32,563 New
MIM
68
MetLife Investment Management
New Jersey
$224K +$80.3K +15,010 +86%
CTB
69
Country Trust Bank
Illinois
$208K
Mirae Asset Global ETFs Holdings
70
Mirae Asset Global ETFs Holdings
Hong Kong
$202K -$11.5K -2,159 -7%
IIM
71
INTECH Investment Management
Florida
$193K -$94.3K -17,631 -39%
PP
72
PDT Partners
New York
$188K +$146K +27,280 New
SPA
73
Sherbrooke Park Advisers
New York
$187K -$151K -28,141 -51%
B
74
Bailard
California
$185K +$144K +26,881 New
JP Morgan Chase
75
JP Morgan Chase
New York
$180K -$983K -183,731 -88%

FULC Hedge Fund Activity: Q2 2025 in Review

122 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Fulcrum Therapeutics (FULC) for Q2 2025, worth a combined $374M — up 152% from $148M a quarter earlier.

Buyers outnumbered sellers: 24 funds opened new FULC positions and 19 closed out — a net gain of 5 holders — while 34 added to existing stakes and 46 trimmed.

The largest buyer was Adage Capital Partners, adding an estimated $8.5M. The largest seller was Nantahala Capital Management, cutting an estimated $2.86M.

  • 122 institutional investors held Fulcrum Therapeutics (FULC) as of Q2 2025, up from 117 in Q1 2025.
  • Funds reported $374M of Fulcrum Therapeutics stock for Q2 2025, up 152% quarter-over-quarter.
  • 24 funds opened new Fulcrum Therapeutics positions in Q2 2025 and 19 closed out, a net change of +5 holders.
  • The largest Fulcrum Therapeutics buyer in Q2 2025 was Adage Capital Partners, an estimated $8.5M added.
  • The largest Fulcrum Therapeutics seller in Q2 2025 was Nantahala Capital Management, an estimated $2.86M sold.

Based on aggregated 13F filings for Q2 2025.