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Amicus Therapeutics

282 hedge funds and large institutions have $2.53B invested in Amicus Therapeutics in 2025 Q1 according to their latest regulatory filings, with 40 funds opening new positions, 113 increasing their positions, 87 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

more funds holding in top 10

Funds holding in top 10:

less first-time investments, than exits

New positions opened: | Existing positions closed:

less ownership

Funds ownership:

2% less funds holding

Funds holding: 287282 (-5)

12% less capital invested

Capital invested by funds: $2.87B → $2.53B (-$349M)

36% less call options, than puts

Call options by funds: $3.21M | Put options by funds: $5.04M

Holders
282
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
5
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$3.21M
Puts
$5.04M
Net Calls
Net Calls Change

Top Buyers

1 +$24.4M
2 +$23.7M
3 +$20.2M
4
Bank of America
Bank of America
North Carolina
+$12.7M
5
Two Sigma Investments
Two Sigma Investments
New York
+$8.94M

Top Sellers

1 -$28.6M
2 -$22.7M
3 -$21.8M
4
JP Morgan Chase
JP Morgan Chase
New York
-$18.9M
5
State Street
State Street
Massachusetts
-$6.87M
Name Holding Trade Value Shares
Change
Change in
Stake
176
$231K
177
$230K
178
$228K
179
$220K
180
$205K
181
$204K
182
$195K
183
$195K
184
$194K
185
$191K
186
$189K
187
$181K
188
$181K
189
$178K
190
$177K
191
$176K
192
$175K
193
$175K
194
$175K
195
$167K
196
$162K
197
$158K
198
$152K
199
$148K
200
$139K