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Amicus Therapeutics
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Overview Fund Activity

281 hedge funds and large institutions have $2.53B invested in Amicus Therapeutics in 2025 Q1 according to their latest regulatory filings, with 41 funds opening new positions, 113 increasing their positions, 86 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
281
Holders Change
-5
Holders Change %
-1.75%
% of All Funds
3.82%
Holding in Top 10
5
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+25%
% of All Funds
0.07%
New
41
Increased
113
Reduced
86
Closed
41
Calls
$3.21M
Puts
$5.05M
Net Calls
-$1.84M
Net Calls Change
-$1.73M

Top Buyers

1
Point72 Asset Management
1
Point72 Asset Management
Connecticut
$24.4M
2
Millennium Management
2
Millennium Management
New York
$27.4M
3
RG
3
Redmile Group
California
$77.8M
4
Bank of America
4
Bank of America
North Carolina
$45.7M
5
Two Sigma Investments
5
Two Sigma Investments
New York
$11.4M

Top Sellers

1
Fiera Capital (Canada)
1
Fiera Capital (Canada)
Quebec, Canada
$0
2
PA
2
Perceptive Advisors
New York
$175M
3
ACA
3
Avoro Capital Advisors
New York
$167M
4
JPMorgan Chase & Co
4
JPMorgan Chase & Co
New York
$39.9M
5
State Street
5
State Street
Massachusetts
$77.7M
Name Holding Trade Value Shares
Change 		Shares
Change %
Thrivent Financial for Lutherans
151
Thrivent Financial for Lutherans
Minnesota
$453K +$363K +44,480 +403%
GAM
152
Gotham Asset Management
New York
$441K +$441K +53,990 New
BC
153
Bridgefront Capital
Texas
$412K +$22.7K +2,780 +6%
HSBC Holdings
154
HSBC Holdings
United Kingdom
$412K +$69.7K +8,536 +20%
MF
155
Magnetar Financial
Illinois
$403K +$239K +29,280 +146%
PD
156
Point72 (DIFC)
United Arab Emirates
$400K +$400K +49,061 New
Vontobel Holding
157
Vontobel Holding
Switzerland
$397K -$14.3K -1,752 -3%
Brown Advisory
158
Brown Advisory
Maryland
$371K – – –
II
159
Inspire Investing
Idaho
$349K -$3.1K -380 -0.9%
Mackenzie Financial
160
Mackenzie Financial
Ontario, Canada
$348K +$164K +20,107 +89%
PA
161
Procyon Advisors
Connecticut
$347K +$148K +18,184 +75%
AQR Capital Management
162
AQR Capital Management
Connecticut
$346K -$390K -47,805 -53%
KK
163
KLP Kapitalforvaltning
Norway
$344K -$55.5K -6,800 -14%
ET
164
Entropy Technologies
New York
$317K +$317K +38,790 New
A
165
AlphaQuest
New York
$305K +$218K +26,679 +249%
Wolverine Trading
166
Wolverine Trading
Illinois
$305K +$305K +36,150 New
Creative Planning
167
Creative Planning
Kansas
$291K -$407K -49,883 -58%
DnB Asset Management
168
DnB Asset Management
Norway
$290K +$25.1K +3,077 +9%
VIA
169
Virtus Investment Advisers
Connecticut
$289K +$165K +20,270 +134%
Stifel Financial
170
Stifel Financial
Missouri
$275K -$445K -54,513 -62%
CIM
171
CIM Investment Management
Pennsylvania
$273K -$6.54K -801 -2%
AIP
172
Ameritas Investment Partners
Nebraska
$250K – – –
Public Employees Retirement Association of Colorado
173
Public Employees Retirement Association of Colorado
Colorado
$246K – – –
TWP
174
Tempus Wealth Planning
California
$241K +$16.2K +1,990 +7%
VF
175
Virtu Financial
New York
$233K +$233K +28,571 New
5 6
7
8 9