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Amicus Therapeutics
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Overview Fund Activity

281 hedge funds and large institutions have $2.53B invested in Amicus Therapeutics in 2025 Q1 according to their latest regulatory filings, with 41 funds opening new positions, 113 increasing their positions, 86 reducing their positions, and 41 closing their positions.

Holders
281
Holders Change
-5
Holders Change %
-1.75%
% of All Funds
3.82%
Holding in Top 10
5
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+25%
% of All Funds
0.07%
New
41
Increased
113
Reduced
86
Closed
41
Calls
$3.21M
Puts
$5.05M
Net Calls
-$1.84M
Net Calls Change
-$1.73M

Top Buyers

1
Point72 Asset Management
1
Point72 Asset Management
Connecticut
$24.4M
2
Millennium Management
2
Millennium Management
New York
$27.4M
3
RG
3
Redmile Group
California
$77.8M
4
Bank of America
4
Bank of America
North Carolina
$45.7M
5
Two Sigma Investments
5
Two Sigma Investments
New York
$11.4M

Top Sellers

1
Fiera Capital (Canada)
1
Fiera Capital (Canada)
Quebec, Canada
$0
2
PA
2
Perceptive Advisors
New York
$175M
3
ACA
3
Avoro Capital Advisors
New York
$167M
4
JPMorgan Chase & Co
4
JPMorgan Chase & Co
New York
$39.9M
5
State Street
5
State Street
Massachusetts
$77.7M
Name Holding Trade Value Shares
Change 		Shares
Change %
AA
101
ALPS Advisors
Colorado
$1.81M -$158K -19,367 -8%
DekaBank Deutsche Girozentrale
102
DekaBank Deutsche Girozentrale
Germany
$1.8M – – –
Universal-Beteiligungs- und Servicegesellschaft
103
Universal-Beteiligungs- und Servicegesellschaft
Germany
$1.74M +$1.74M +212,745 New
California State Teachers Retirement System (CalSTRS)
104
California State Teachers Retirement System (CalSTRS)
California
$1.7M -$38.4K -4,700 -2%
State of New Jersey Common Pension Fund D
105
State of New Jersey Common Pension Fund D
New Jersey
$1.69M -$109K -13,379 -6%
Marshall Wace
106
Marshall Wace
United Kingdom
$1.6M +$1M +123,145 +169%
ACM
107
Aquatic Capital Management
Illinois
$1.55M -$370K -45,330 -19%
JFG
108
Jefferies Financial Group
New York
$1.53M +$1.53M +187,897 New
Envestnet Asset Management
109
Envestnet Asset Management
Illinois
$1.52M -$1.95M -238,864 -56%
SEI Investments
110
SEI Investments
Pennsylvania
$1.52M -$271K -33,226 -15%
MIM
111
MetLife Investment Management
New Jersey
$1.42M -$44.9K -5,498 -3%
IIM
112
INTECH Investment Management
Florida
$1.39M +$377K +46,218 +37%
CM
113
Caption Management
Oklahoma
$1.38M +$609K +74,651 +79%
Wells Fargo
114
Wells Fargo
California
$1.34M -$2.24M -274,753 -63%
Manulife (Manufacturers Life Insurance)
115
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$1.33M +$47.6K +5,835 +4%
EGM
116
Engineers Gate Manager
New York
$1.32M +$473K +57,943 +55%
BT
117
Banque Transatlantique
France
$1.26M +$1.26M +166,491 New
Canada Pension Plan Investment Board
118
Canada Pension Plan Investment Board
Ontario, Canada
$1.21M +$1.21M +148,700 New
WCM
119
Wedge Capital Management
North Carolina
$1.17M -$367K -45,007 -24%
CF
120
Corebridge Financial
Texas
$1.17M -$17.4K -2,131 -1%
Russell Investments Group
121
Russell Investments Group
United Kingdom
$1.16M +$729K +89,287 +168%
First Trust Advisors
122
First Trust Advisors
Illinois
$1.06M -$243K -29,812 -19%
EAM
123
Erste Asset Management
Austria
$985K – – –
SAM
124
Sectoral Asset Management
Quebec, Canada
$878K -$229K -28,035 -21%
XT
125
XTX Topco
Cayman Islands
$871K +$557K +68,245 +177%
3 4
5
6 7